SV2B

Description		synaptic vesicle glycoprotein 2B
Image
GO Annotations	Cellular Component	Acrosomal Vesicle Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse
	Molecular Function	Protein Binding Transmembrane Transporter Activity
	Biological Process	Neurotransmitter Transport Chemical Synaptic Transmission Transmembrane Transport Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Synaptic Vesicle Exocytosis
Pathways		Toxicity of botulinum toxin type D (botD) Toxicity of botulinum toxin type A (botA) Toxicity of botulinum toxin type F (botF) Toxicity of botulinum toxin type E (botE)
Drugs
Diseases
GWAS		Age-related hearing impairment ( 24939585) Gout (normal type) ( 32238385) Iris color (a* coordinate) ( 30895295) Iris color (b* coordinate) ( 30895295) Metabolite levels ( 19043545 23823483) Neuritic plaque ( 31497858) Primary sclerosing cholangitis ( 27992413) Rosacea symptom severity ( 29771307)
Novel Interacting Genes		2 novel interacting genes: HSFY1 SYT1
Interacting Genes		2 interacting genes: HSFY1 SYT1
Entrez ID		9899
HPRD ID		11765
Ensembl ID		ENSG00000185518
Uniprot IDs		Q7L1I2
PDB IDs		8UO8 9F1R 9F2B 9F2J 9F2Y 9F3C
Enriched GO Terms of Interacting Partners?		Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Synchronous Neurotransmitter Secretion Positive Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Syntaxin-3 Binding Positive Regulation Of Synaptic Vesicle Exocytosis Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Spontaneous Neurotransmitter Secretion Chromaffin Granule Membrane Clathrin-sculpted Glutamate Transport Vesicle Membrane Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Dopamine Secretion Clathrin-sculpted Monoamine Transport Vesicle Membrane Calcium Ion-regulated Exocytosis Of Neurotransmitter Calcium-dependent Activation Of Synaptic Vesicle Fusion Positive Regulation Of Catecholamine Secretion Positive Regulation Of Neurotransmitter Secretion Neuron Projection Terminus Dense Core Granule Positive Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Dendrite Extension Detection Of Calcium Ion Calcium Ion Sensor Activity Positive Regulation Of Vesicle Fusion Syntaxin-1 Binding Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Low-density Lipoprotein Particle Receptor Binding Exocytic Vesicle Regulation Of Dopamine Secretion Protein Heterooligomerization Presynaptic Cytosol Postsynaptic Cytosol Excitatory Synapse Calcium-ion Regulated Exocytosis Regulation Of Vesicle Fusion Clathrin Binding Synaptic Vesicle Exocytosis Regulation Of Catecholamine Secretion Regulation Of Calcium Ion-dependent Exocytosis Neurotransmitter Secretion Presynaptic Active Zone Hippocampal Mossy Fiber To CA3 Synapse Syntaxin Binding Positive Regulation Of Regulated Secretory Pathway Calcium-dependent Phospholipid Binding Molecular Condensate Scaffold Activity Regulation Of Synaptic Vesicle Exocytosis Transport Vesicle Membrane Phosphatidylserine Binding Vesicle Docking
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