CEP170

Description		centrosomal protein 170
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GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Spindle Cytosol Cytoskeleton Microtubule Ciliary Basal Body Centriolar Subdistal Appendage
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Bronchopulmonary dysplasia ( 23897914) Chromium levels ( 26025379) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Estimated glomerular filtration rate ( 31015462) Lung cancer in ever smokers ( 28604730) Mental health study participation (completed survey) ( 31263887) Metabolite levels ( 23823483) Red cell distribution width ( 28957414 32888494) Schizophrenia ( 23974872) Smoking behaviour (cigarettes smoked per day) ( 31217584) Systemising ( 31508503)
Novel Interacting Genes		9 novel interacting genes: CEBPA NDEL1 PPP1CA PTEN SDCCAG8 SNAPIN SRPK2 VAV2 YWHAG
Interacting Genes		9 interacting genes: CEBPA NDEL1 PPP1CA PTEN SDCCAG8 SNAPIN SRPK2 VAV2 YWHAG
Entrez ID		9859
HPRD ID		17172
Ensembl ID		ENSG00000143702
Uniprot IDs		Q5SW79
PDB IDs		4JON
Enriched GO Terms of Interacting Partners?		Organelle Organization Developmental Maturation Intracellular Signaling Cassette Cellular Response To Xenobiotic Stimulus RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Developmental Process Presynapse Protein Stabilization Protein Dephosphorylation Phosphatase Activity Regulation Of Protein Stability RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Protein Serine/threonine Phosphatase Activity Cytosol Regulation Of Plasma Membrane Bounded Cell Projection Organization Negative Regulation Of Synaptic Vesicle Clustering Regulation Of Cell Projection Organization Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Central Nervous System Neuron Axonogenesis Cell Migration Cell Projection Organization Microtubule-based Process Regulation Of Cellular Component Size Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cell Size Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Vesicle Cytoskeletal Trafficking Retrograde Axonal Transport Positive Regulation Of Late Endosome To Lysosome Transport Vesicle Transport Along Microtubule Lysosome Localization Axon Cytoplasm Axonal Transport Axo-dendritic Transport Organelle Transport Along Microtubule Neurofilament Cytoskeleton Intracellular Signal Transduction Regulation Of Neuron Projection Development Lung Development Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Translational Initiation Negative Regulation Of Protein Phosphorylation Cell Motility Establishment Of Vesicle Localization CHOP-C/EBP Complex Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled
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