DNAJC6

Description		DnaJ heat shock protein family (Hsp40) member C6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Postsynaptic Density Clathrin-coated Vesicle Cytoplasmic Vesicle Vesicle Intracellular Membrane-bounded Organelle Synapse Extrinsic Component Of Presynaptic Endocytic Zone Membrane
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity SH3 Domain Binding Clathrin Binding Heat Shock Protein Binding Clathrin Heavy Chain Binding
	Biological Process	Synaptic Vesicle Uncoating Synaptic Vesicle Recycling Intracellular Transport Clathrin Coat Disassembly Clathrin-dependent Endocytosis Regulation Of Clathrin Coat Assembly Regulation Of Clathrin-dependent Endocytosis
Pathways		Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Anticoagulant levels ( 22216198) Idiopathic osteonecrosis of the femoral head ( 28000841)
Novel Interacting Genes		3 novel interacting genes: AP2A2 BAG2 CLTC
Interacting Genes		3 interacting genes: AP2A2 BAG2 CLTC
Entrez ID		9829
HPRD ID		16326
Ensembl ID		ENSG00000116675
Uniprot IDs		O75061
PDB IDs
Enriched GO Terms of Interacting Partners?		Endolysosome Membrane Disordered Domain Specific Binding Clathrin-coated Endocytic Vesicle Clathrin-dependent Endocytosis Clathrin-coated Endocytic Vesicle Membrane Receptor Internalization Clathrin-coated Pit Receptor-mediated Endocytosis Dendritic Microtubule Postsynaptic Neurotransmitter Receptor Internalization Clathrin Coat Of Trans-Golgi Network Vesicle Vesicle Uncoating Regulation Of Hyaluronan Biosynthetic Process Negative Regulation Of Hyaluronan Biosynthetic Process Clathrin Complex Clathrin Coat Clathrin Coat Of Coated Pit Clathrin Light Chain Binding Clathrin Coat Disassembly Amyloid-beta Clearance By Transcytosis Clathrin Adaptor Complex AP-2 Adaptor Complex Endocytosis Protein Kinase Binding Transferrin Transport Adenyl-nucleotide Exchange Factor Activity Intracellular Protein Transport Mitotic Spindle Microtubule Clathrin Adaptor Activity Transcytosis Ubiquitin-specific Protease Binding Clathrin Coat Assembly Import Into Cell Low-density Lipoprotein Particle Receptor Binding Amyloid-beta Clearance Positive Regulation Of Protein Processing Positive Regulation Of Protein Maturation Membrane Coat Negative Regulation Of Protein Localization To Plasma Membrane Protein Folding Chaperone Complex Protein Depolymerization Synaptic Vesicle Endocytosis Cytoplasmic Vesicle Presynaptic Endocytosis Regulation Of Mitotic Spindle Organization Iron Ion Transport Tau Protein Binding Ficolin-1-rich Granule Membrane Regulation Of Protein Processing Regulation Of Protein Maturation
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