PTDSS1

Description		phosphatidylserine synthase 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Transferase Activity L-serine-phosphatidylethanolamine Phosphatidyltransferase Activity L-serine-phosphatidylcholine Phosphatidyltransferase Activity
	Biological Process	Lipid Metabolic Process Phosphatidylserine Biosynthetic Process Phospholipid Biosynthetic Process
Pathways		Synthesis of PS
Drugs		Phosphatidyl serine
Diseases
GWAS		Huntington's disease progression ( 28642124) Obesity-related traits ( 23251661) Peripheral arterial disease x type 2 diabetes interaction ( 32541925)
Novel Interacting Genes		3 novel interacting genes: CREB3 PTEN TSHR
Interacting Genes		3 interacting genes: CREB3 PTEN TSHR
Entrez ID		9791
HPRD ID		17926
Ensembl ID		ENSG00000156471
Uniprot IDs		P48651
PDB IDs		9B4E 9B4F 9B4G
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Cellular Response To Thyrotropin-releasing Hormone Thyroid-stimulating Hormone Receptor Activity Thyroid-stimulating Hormone Signaling Pathway Response To Thyrotropin-releasing Hormone Positive Regulation Of Deacetylase Activity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Regulation Of Cell Population Proliferation Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol Phosphate Phosphatase Activity Cellular Response To Glycoprotein Release From Viral Latency Regulation Of Synaptic Vesicle Clustering CCR1 Chemokine Receptor Binding Negative Regulation Of Cell Cycle Negative Regulation Of Peptidyl-serine Phosphorylation Postsynaptic Density Assembly Locomotor Rhythm Cellular Response To Electrical Stimulus Ubiquitin Ligase Activator Activity Spindle Assembly Involved In Female Meiosis Postsynaptic Specialization Assembly Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size Presynaptic Membrane Organization Schmidt-Lanterman Incisure Anaphase-promoting Complex Binding Forebrain Morphogenesis Negative Regulation Of Excitatory Postsynaptic Potential Presynaptic Membrane Assembly Protein-hormone Receptor Activity CAMP Response Element Binding Protein Binding Maternal Behavior Phosphatidylinositol-3-phosphate Phosphatase Activity Prepulse Inhibition Meiotic Spindle Assembly Myelin Maintenance Parental Behavior Induction Of Positive Chemotaxis Synapse Maturation Negative Regulation Of Epithelial Cell Migration Postsynaptic Density Organization Negative Regulation Of Focal Adhesion Assembly
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