USP6NL

Description		USP6 N-terminal like
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Golgi Organization Virion Assembly Retrograde Transport, Plasma Membrane To Golgi Positive Regulation Of GTPase Activity Plasma Membrane To Endosome Transport Regulation Of Cilium Assembly Regulation Of Golgi Organization
Pathways		Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) LDL levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429) Obesity-related traits ( 23251661)
Novel Interacting Genes		6 novel interacting genes: ACTA1 ACTN4 APP EPS8 GRB2 RAB5A
Interacting Genes		6 interacting genes: ACTA1 ACTN4 APP EPS8 GRB2 RAB5A
Entrez ID		9712
HPRD ID		08957
Ensembl ID		ENSG00000148429
Uniprot IDs		Q92738 X6RAB3
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Exosome Regulation Of Long-term Neuronal Synaptic Plasticity Ephrin Receptor Binding Cell Development Cell Body Actin Cytoskeleton Stress Fiber Actin Filament-based Process Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Platelet Alpha Granule Lumen Cell Projection Actin Cytoskeleton Organization Amyloid-beta Complex Regulation Of Neuronal Synaptic Plasticity Growth Cone Lamellipodium Adult Locomotory Behavior Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Supramolecular Fiber Organization Positive Regulation Of Toll Signaling Pathway Endocytosis Positive Regulation Of Reactive Oxygen Species Metabolic Process Glial Cell Development Regulation Of Cellular Component Size Receptor Internalization Guanyl-nucleotide Exchange Factor Adaptor Activity Supramolecular Fiber Organization Muscle Cell Development Regulation Of Non-canonical NF-kappaB Signal Transduction Nucleoside Binding Positive Regulation Of Sodium:proton Antiporter Activity Acetylcholine Receptor Activator Activity Regulation Of Plasma Membrane Bounded Cell Projection Organization PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Regulation Of Reactive Oxygen Species Metabolic Process Growth Cone Filopodium Growth Cone Lipoprotein Particle Import Into Cell Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length
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