CLCA2

Description		chloride channel accessory 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Cytosol Plasma Membrane Basal Plasma Membrane Membrane Cell Junction Nuclear Membrane Anchoring Junction
	Molecular Function	Metalloendopeptidase Activity Intracellularly Calcium-gated Chloride Channel Activity Chloride Channel Activity Peptidase Activity Metallopeptidase Activity Ligand-gated Monoatomic Ion Channel Activity Hydrolase Activity Metal Ion Binding
	Biological Process	Proteolysis Monoatomic Ion Transport Chloride Transport Cell Adhesion Monoatomic Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways		Stimuli-sensing channels
Drugs
Diseases
GWAS		Crohn's disease-related phenotypes ( 25557950) Hallux valgus ( 32131869)
Novel Interacting Genes		1 novel interacting genes: ITGB4
Interacting Genes		1 interacting genes: ITGB4
Entrez ID		9635
HPRD ID		04923
Ensembl ID		ENSG00000137975
Uniprot IDs		Q9UQC9
PDB IDs
Enriched GO Terms of Interacting Partners?		Hemidesmosome Assembly Hemidesmosome Nail Development Peripheral Nervous System Myelin Formation Neuregulin Binding Trophoblast Cell Migration Skin Morphogenesis Myelin Assembly Insulin-like Growth Factor I Binding Mesodermal Cell Differentiation Myelination In Peripheral Nervous System Filopodium Assembly Integrin Complex Cell Adhesion Mediated By Integrin Cell-substrate Junction Organization Cell-substrate Junction Assembly Cell Leading Edge Basal Plasma Membrane G Protein-coupled Receptor Binding Basement Membrane Myelination Axon Ensheathment Integrin-mediated Signaling Pathway Cell-matrix Adhesion Ameboidal-type Cell Migration Integrin Binding Cell-substrate Adhesion Receptor Complex Cell Junction Response To Wounding Cell Junction Assembly Nuclear Membrane Autophagy Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Anchoring Junction Focal Adhesion Cell Junction Organization
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