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CREB5
Description
cAMP responsive element binding protein 5
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Extracellular Exosome
Molecular Function
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
CAMP Response Element Binding
Identical Protein Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS
Adolescent idiopathic scoliosis (
31417091
)
Age-related cognitive decline (global cognition) (slope of z-scores) (
30954325
)
Age-related cognitive decline (memory) (slope of z-scores) (
30954325
)
Airflow obstruction (
22837378
)
Alanine aminotransferase levels in non-alcoholic fatty liver disease (
31311600
)
Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals (
22959728
)
Anxiety in major depressive disorder (
24047446
)
Appendicular lean mass (
33097823
)
Asthma (
31959851
)
Asthma (childhood onset) (
31036433
)
Atrial fibrillation (
29892015
30061737
)
Attention deficit hyperactivity disorder (
18839057
)
Basophil count (
32888494
)
Basophil percentage of white cells (
32888494
)
Blond vs. brown/black hair color (
30531825
)
Breast cancer (
29059683
)
Cataracts (
34127677
)
Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) (
31372216
)
Crohn's disease (
23128233
)
Diabetic retinopathy (
21441570
)
Emphysema annual change measurement in smokers (percent low attenuation area) (
31324189
)
Eosinophil percentage of granulocytes (
27863252
)
Ferritin levels (
33491795
)
Granulocyte count (
27863252
)
Granulocyte percentage of myeloid white cells (
27863252
)
Hand grip strength (
29691431
)
Heel bone mineral density (
28869591
30598549
)
Height (
28552196
)
Hip circumference adjusted for BMI (
34021172
)
Lymphocyte percentage of white cells (
27863252
32888494
)
Monocyte count (
32888494
)
Monocyte percentage of white cells (
27863252
32888494
)
Myeloid white cell count (
27863252
)
Neutrophil count (
27863252
32888494
29403010
)
Neutrophil percentage of granulocytes (
27863252
)
Neutrophil percentage of white cells (
32888494
27863252
)
Peginterferon alfa-2a treatment response in chronic hepatitis B infection (
30972912
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Pulse pressure (
27841878
30578418
)
Serum thyroid-stimulating hormone levels (
25436638
)
Smoking behaviour (cigarettes smoked per day) (
31217584
)
Sum basophil neutrophil counts (
27863252
)
Sum neutrophil eosinophil counts (
27863252
)
TPE interval (resting) (
32386560
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
White blood cell count (
29403010
32888494
27863252
)
White blood cell count (basophil) (
27863252
)
Novel Interacting Genes
135 novel interacting genes:
ADAMTSL4
AJUBA
AKAP8L
ALPP
ANAPC11
ATF2
CDPF1
CERCAM
CIB4
CNFN
COL8A1
CYP21A2
CYSRT1
EFEMP2
FBLN1
FHL3
FOS
FOSB
FOSL1
FOSL2
FRS3
FST
HOXA1
HSD3B7
ID3
IGFBP6
INTS11
JDP2
JUN
KIFC3
KPRP
KRT15
KRT31
KRT40
KRT83
KRT85
KRT86
KRTAP1-1
KRTAP1-3
KRTAP1-5
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-3
KRTAP19-2
KRTAP19-3
KRTAP19-5
KRTAP19-6
KRTAP2-3
KRTAP2-4
KRTAP22-1
KRTAP3-1
KRTAP3-2
KRTAP4-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP5-11
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-7
KRTAP5-9
KRTAP6-1
KRTAP6-2
KRTAP6-3
KRTAP7-1
KRTAP8-1
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LCE1C
LCE1F
LCE2A
LCE2C
LCE4A
LCE5A
LGALS13
LITAF
LMX1B
MDFI
MGAT5B
MLLT6
MMADHC
MTUS2
NADSYN1
NBPF19
NOTCH2NLA
PCSK5
PLA2G10
PRDM14
PRR22
RBCK1
RBP3
RBPMS
RCHY1
RGS17
RGS20
RIMBP3
RNF144B
RNF208
SIVA1
SNAPC5
SPATA12
SPOP
SPOPL
SPRED1
SPRY1
SPRY2
SPRY3
SPRY4
SSC4D
TP53BP1
TRAF2
TRIM23
TRIM27
TRIM42
TRIP6
TSGA10
TSPAN4
TSR2
UFSP1
UNKL
WWOX
ZMAT5
ZNF330
Interacting Genes
135 interacting genes:
ADAMTSL4
AJUBA
AKAP8L
ALPP
ANAPC11
ATF2
CDPF1
CERCAM
CIB4
CNFN
COL8A1
CYP21A2
CYSRT1
EFEMP2
FBLN1
FHL3
FOS
FOSB
FOSL1
FOSL2
FRS3
FST
HOXA1
HSD3B7
ID3
IGFBP6
INTS11
JDP2
JUN
KIFC3
KPRP
KRT15
KRT31
KRT40
KRT83
KRT85
KRT86
KRTAP1-1
KRTAP1-3
KRTAP1-5
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-3
KRTAP19-2
KRTAP19-3
KRTAP19-5
KRTAP19-6
KRTAP2-3
KRTAP2-4
KRTAP22-1
KRTAP3-1
KRTAP3-2
KRTAP4-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP5-11
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-7
KRTAP5-9
KRTAP6-1
KRTAP6-2
KRTAP6-3
KRTAP7-1
KRTAP8-1
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LCE1C
LCE1F
LCE2A
LCE2C
LCE4A
LCE5A
LGALS13
LITAF
LMX1B
MDFI
MGAT5B
MLLT6
MMADHC
MTUS2
NADSYN1
NBPF19
NOTCH2NLA
PCSK5
PLA2G10
PRDM14
PRR22
RBCK1
RBP3
RBPMS
RCHY1
RGS17
RGS20
RIMBP3
RNF144B
RNF208
SIVA1
SNAPC5
SPATA12
SPOP
SPOPL
SPRED1
SPRY1
SPRY2
SPRY3
SPRY4
SSC4D
TP53BP1
TRAF2
TRIM23
TRIM27
TRIM42
TRIP6
TSGA10
TSPAN4
TSR2
UFSP1
UNKL
WWOX
ZMAT5
ZNF330
Entrez ID
9586
HPRD ID
09896
Ensembl ID
ENSG00000146592
Uniprot IDs
Q02930
PDB IDs
Enriched GO Terms of Interacting Partners
?
Intermediate Filament
Keratin Filament
Keratinization
Epidermis Development
Hair Cycle
Cytosol
Protein Binding
Structural Constituent Of Skin Epidermis
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Identical Protein Binding
Negative Regulation Of Lens Fiber Cell Differentiation
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Intermediate Filament-based Process
Intermediate Filament Cytoskeleton Organization
Transcription Factor AP-1 Complex
Intermediate Filament Organization
Regulation Of Lens Fiber Cell Differentiation
Negative Regulation Of Ras Protein Signal Transduction
Negative Regulation Of ERK1 And ERK2 Cascade
RNA Polymerase II Transcription Regulator Complex
CAMP Response Element Binding
Cellular Response To Anisomycin
Tissue Development
Response To Anisomycin
NK T Cell Differentiation
Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Ras Protein Signal Transduction
Elastic Fiber
Negative Regulation Of Epithelial Cell Differentiation
Tagcloud
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