KIF20B

Description		kinesin family member 20B
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Kinesin Complex Microtubule Microtubule Cytoskeleton Axon Growth Cone Midbody Ciliary Basal Body Cell Projection Intercellular Bridge Perinuclear Region Of Cytoplasm Spindle Midzone Contractile Ring Mitotic Spindle Pole Mitotic Spindle Midzone
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity ATP Hydrolysis Activity Protein Homodimerization Activity WW Domain Binding
	Biological Process	Neural Tube Closure Microtubule-based Movement Regulation Of Mitotic Nuclear Division Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cytokinesis Protein Localization To Microtubule Neuron Projection Morphogenesis Cell Division Regulation Of Cell Cycle Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Protein Transport Positive Regulation Of Mitotic Cytokinetic Process Regulation Of Establishment Of Cell Polarity Regulation Of Neuron Migration Positive Regulation Of Neuron Migration
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Distal colorectal cancer ( 33632709) Distal/Left-sided colorectal cancer ( 33632709) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy) ( 24554482)
Novel Interacting Genes		3 novel interacting genes: CDK1 PIN1 PTEN
Interacting Genes		3 interacting genes: CDK1 PIN1 PTEN
Entrez ID		9585
HPRD ID		09268
Ensembl ID		ENSG00000138182
Uniprot IDs		Q96Q89
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Ligase Activator Activity Microtubule Polymerization Microtubule Cytoskeleton Organization Microtubule Polymerization Or Depolymerization Regulation Of Mitotic Cell Cycle Protein Polymerization Regulation Of Organ Growth Microtubule-based Process Regulation Of Cell Cycle Process Beta-catenin Binding Intracellular Signaling Cassette Pronuclear Fusion Cis-trans Isomerase Activity Negative Regulation Of Synaptic Vesicle Clustering Cytoskeleton Organization Mitotic DNA-templated DNA Replication Negative Regulation Of Mitotic Cell Cycle Phase Transition Cyclin B1-CDK1 Complex Regulation Of Protein Localization To Nucleus Cyclin A1-CDK1 Complex Midbody Cyclin A2-CDK1 Complex Regulation Of Cell Cycle Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Mitotic DNA Replication DNA Synthesis Involved In Mitotic DNA Replication Negative Regulation Of Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Cyclin-dependent Protein Kinase Activity Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Protein Stabilization Regulation Of Schwann Cell Differentiation Rhythmic Process Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Synapse Organization Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Protein Modification Process Negative Regulation Of Cell Cycle Process Thymidine Biosynthetic Process Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Thymidine Metabolic Process Intracellular Signal Transduction
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