BABAM2

Description		BRISC and BRCA1 A complex member 2
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GO Annotations	Cellular Component	Nuclear Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol BRCA1-A Complex BRISC Complex
	Molecular Function	Peroxisome Targeting Sequence Binding Tumor Necrosis Factor Receptor Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	DNA Repair Regulation Of DNA Repair Double-strand Break Repair Chromatin Organization Apoptotic Process DNA Damage Response Mitotic G2 DNA Damage Checkpoint Signaling Signal Transduction Response To Ionizing Radiation Negative Regulation Of Apoptotic Process Mitotic G2/M Transition Checkpoint Positive Regulation Of DNA Repair Cell Division Protein K63-linked Deubiquitination Cellular Response To Ionizing Radiation Regulation Of DNA Damage Checkpoint
Pathways		Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Estimated glomerular filtration rate ( 31152163) Intraocular pressure ( 29617998) Low density lipoprotein cholesterol levels ( 33339817) Urate levels ( 31578528) Uterine fibroids ( 31649266)
Novel Interacting Genes		8 novel interacting genes: BABAM1 GFI1B NCOA3 PPDPF SUMO2 UBC UBE2D1 VRK2
Interacting Genes		8 interacting genes: BABAM1 GFI1B NCOA3 PPDPF SUMO2 UBC UBE2D1 VRK2
Entrez ID		9577
HPRD ID		08498
Ensembl ID		ENSG00000158019
Uniprot IDs		Q9NXR7
PDB IDs		6H3C 6R8F 8PVY 8PY2
Enriched GO Terms of Interacting Partners?		Protein Tag Activity TORC1 Signaling Organelle Envelope
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