ENTPD5

Description		ectonucleoside triphosphate diphosphohydrolase 5 (inactive)
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum
	Molecular Function	GDP Phosphatase Activity Protein Binding Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity CDP Phosphatase Activity ADP Phosphatase Activity UDP Phosphatase Activity IDP Phosphatase Activity
	Biological Process	UDP-alpha-D-glucose Metabolic Process UDP Catabolic Process Protein Glycosylation Protein N-linked Glycosylation 'de Novo' Post-translational Protein Folding
Pathways		Phosphate bond hydrolysis by NTPDase proteins Purinergic signaling in leishmaniasis infection
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Refractive error ( 32231278) Serum uric acid levels ( 29559957)
Novel Interacting Genes		2 novel interacting genes: MXI1 PRKCA
Interacting Genes		2 interacting genes: MXI1 PRKCA
Entrez ID		957
HPRD ID		16015
Ensembl ID		ENSG00000187097
Uniprot IDs		G3V4I0 O75356
PDB IDs
Enriched GO Terms of Interacting Partners?		Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Angiotensin-activated Signaling Pathway Histone H3T6 Kinase Activity Alphav-beta3 Integrin-PKCalpha Complex Protein Kinase C Signaling Regulation Of Angiotensin-activated Signaling Pathway Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Desmosome Assembly Mitotic Nuclear Membrane Disassembly Diacylglycerol Binding Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Desmosome Organization Positive Regulation Of Bone Resorption Positive Regulation Of Macrophage Differentiation Membrane Disassembly Nuclear Membrane Disassembly Response To Phorbol 13-acetate 12-myristate Negative Regulation Of Glial Cell Apoptotic Process Response To Corticosterone Diacylglycerol-dependent Serine/threonine Kinase Activity Anatomical Structure Formation Involved In Morphogenesis Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Renal Sodium Ion Absorption Blastocyst Formation Renal Sodium Ion Transport Regulation Of Macrophage Differentiation Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Platelet Aggregation Signal Transduction Involved In Regulation Of Gene Expression Regulation Of Bone Resorption Central Nervous System Neuron Axonogenesis Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Cytokine Production Involved In Inflammatory Response Response To Mineralocorticoid Regulation Of Bone Remodeling Renal Absorption Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cytokine Production Involved In Inflammatory Response Nuclear Membrane Organization Regulation Of Platelet Activation
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