GTPBP1

Description		GTP binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Exosome (RNase Complex) Cytoplasm Cytosol Membrane
	Molecular Function	TRNA Binding Nucleotide Binding RNA Binding Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Alpha-aminoacyl-tRNA Binding
	Biological Process	Cytoplasmic Translation Translational Elongation Immune Response Signal Transduction GTP Metabolic Process Positive Regulation Of MRNA Catabolic Process RNA Surveillance
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) C-reactive protein levels ( 30388399) Diverticular disease ( 30177863) Hand grip strength ( 29691431) Hip circumference adjusted for BMI ( 34021172) Mean reticulocyte volume ( 32888494) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Novel Interacting Genes		7 novel interacting genes: APP C7orf25 CACNA1I CEBPA DNAL4 LRP1 WEE2-AS1
Interacting Genes		7 interacting genes: APP C7orf25 CACNA1I CEBPA DNAL4 LRP1 WEE2-AS1
Entrez ID		9567
HPRD ID		03765
Ensembl ID		ENSG00000100226
Uniprot IDs		O00178
PDB IDs
Enriched GO Terms of Interacting Partners?		Astrocyte Activation Involved In Immune Response Heparan Sulfate Proteoglycan Binding Apolipoprotein Binding Regulation Of Amyloid-beta Clearance Astrocyte Activation Positive Regulation Of Protein Catabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Response To Amyloid-beta Positive Regulation Of Toll Signaling Pathway Clathrin-coated Pit Cellular Response To Amyloid-beta Regulation Of Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Transcytosis Alpha-2 Macroglobulin Receptor Activity Apolipoprotein Receptor Activity Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Memory Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization CHOP-C/EBP Complex Response To Vitamin B2 C/EBP Complex Positive Regulation Of Reverse Cholesterol Transport Regulation Of Transcytosis Lipoprotein Particle Receptor Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Inflammatory Response Axon Midline Choice Point Recognition Cell Activation Involved In Immune Response Positive Regulation Of Amyloid Fibril Formation Cell Maturation Positive Regulation Of Endocytosis
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