H6PD

Description		hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Sarcoplasmic Reticulum
	Molecular Function	Catalytic Activity Glucose-6-phosphate Dehydrogenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On CH-OH Group Of Donors Hydrolase Activity 6-phosphogluconolactonase Activity Carbohydrate Binding Glucose 1-dehydrogenase (NAD+) Activity Glucose 1-dehydrogenase (NADP+) Activity Glucose 1-dehydrogenase [NAD(P)+] Activity NADP Binding
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Pentose-phosphate Shunt NADP+ Metabolic Process Pentose-phosphate Shunt, Oxidative Branch Response To Nutrient Levels Response To Alcohol Regulation Of Cortisol Biosynthetic Process
Pathways
Drugs		NADH
Diseases		Cortisone reductase deficiency (CRD)
GWAS		Blood protein levels ( 30072576) Height ( 23563607 25282103 31562340) Hip circumference ( 28552196) Hip circumference adjusted for BMI ( 34021172)
Novel Interacting Genes		1 novel interacting genes: TNFRSF4
Interacting Genes		1 interacting genes: TNFRSF4
Entrez ID		9563
HPRD ID		00681
Ensembl ID		ENSG00000049239
Uniprot IDs		O95479
PDB IDs		8EM2
Enriched GO Terms of Interacting Partners?		Regulation Of B Cell Proliferation Positive Regulation Of Immunoglobulin Production Positive Regulation Of Lymphocyte Proliferation Lymphocyte Proliferation Regulation Of B Cell Activation T Cell Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Leukocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Symbiont Entry Into Host Cell Tumor Necrosis Factor Receptor Activity Mononuclear Cell Proliferation Virus Receptor Activity Regulation Of Immunoglobulin Production Biological Process Involved In Interaction With Host Positive Regulation Of B Cell Activation Positive Regulation Of B Cell Proliferation Positive Regulation Of Leukocyte Proliferation
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