AKAP5

Description		A-kinase anchoring protein 5
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GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Protein Serine/threonine Phosphatase Complex Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Membrane Dendrite Dendrite Membrane Cell Projection Dendritic Spine Membrane Raft Synapse Postsynaptic Membrane Excitatory Synapse Postsynaptic Recycling Endosome Postsynaptic Recycling Endosome Membrane
	Molecular Function	Protein Binding Calmodulin Binding Adenylate Cyclase Binding SH3 Domain Binding Protein Phosphatase 2B Binding Beta-2 Adrenergic Receptor Binding Protein Kinase A Regulatory Subunit Binding Glutamate Receptor Binding GABA Receptor Binding Protein Kinase A Binding Molecular Adaptor Activity Scaffold Protein Binding
	Biological Process	Signal Transduction Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Chemical Synaptic Transmission Regulation Of Protein Kinase A Signaling Calcineurin-NFAT Signaling Cascade Positive Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Calcium Ion Import Across Plasma Membrane Positive Regulation Of Endosome To Plasma Membrane Protein Transport
Pathways		Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Trafficking of AMPA receptors ROBO receptors bind AKAP5 ROBO receptors bind AKAP5
Drugs
Diseases
GWAS
Novel Interacting Genes		21 novel interacting genes: ADRB2 CALM1 DLG1 DLG4 FOS GABRB1 GABRB3 IQGAP1 JUN KCNJ2 MDM2 PPP3CA PRKAR1A PRKAR2A PRKAR2B PRKCA RET ROPN1 ROPN1L TP53 TRPV1
Interacting Genes		21 interacting genes: ADRB2 CALM1 DLG1 DLG4 FOS GABRB1 GABRB3 IQGAP1 JUN KCNJ2 MDM2 PPP3CA PRKAR1A PRKAR2A PRKAR2B PRKCA RET ROPN1 ROPN1L TP53 TRPV1
Entrez ID		9495
HPRD ID		05255
Ensembl ID		ENSG00000179841
Uniprot IDs		P24588 Q6PG46
PDB IDs		2H9R 3LL8 5NIN
Enriched GO Terms of Interacting Partners?		Regulation Of Membrane Potential Intracellular Signal Transduction Response To Metal Ion Signal Transduction Intracellular Signaling Cassette Regulation Of Intracellular Signal Transduction CAMP-dependent Protein Kinase Regulator Activity Regulation Of Biological Quality Regulation Of System Process CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Inhibitor Activity Regulation Of CAMP/PKA Signal Transduction Regulation Of Muscle System Process Response To Calcium Ion Protein Kinase A Catalytic Subunit Binding Regulation Of Multicellular Organismal Process Dendritic Spine Regulation Of Signal Transduction Ubiquitin Protein Ligase Binding Developmental Process Cellular Response To Metal Ion CAMP Binding Plasma Membrane System Process Glutamatergic Synapse Cellular Response To Actinomycin D Positive Regulation Of Angiotensin-activated Signaling Pathway Negative Regulation Of CAMP/PKA Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Response To Steroid Hormone Enzyme Binding Response To Toxic Substance Regulation Of Postsynaptic Membrane Potential Protein Domain Specific Binding Postsynaptic Membrane Response To Actinomycin D Extracellular Ligand-gated Monoatomic Ion Channel Activity Muscle System Process Cellular Response To UV-C Regulation Of Angiotensin-activated Signaling Pathway Positive Regulation Of Glomerulus Development Learning Or Memory Positive Regulation Of Cell Communication Positive Regulation Of Signaling Ciliary Base Modulation Of Chemical Synaptic Transmission Transcription Factor AP-1 Complex Cellular Response To Histamine Response To Xenobiotic Stimulus
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