CAPZA3

Description		capping actin protein of muscle Z-line subunit alpha 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoskeleton F-actin Capping Protein Complex Membrane Cortical Cytoskeleton Sperm Head
	Molecular Function	Actin Binding Actin Filament Binding
	Biological Process	Actin Filament Organization Cytoplasm Organization Spermatid Development Actin Cytoskeleton Organization Barbed-end Actin Filament Capping Actin Filament Capping
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Personality dimensions ( 23903073)
Novel Interacting Genes		2 novel interacting genes: ACTG1 CAPZA2
Interacting Genes		2 interacting genes: ACTG1 CAPZA2
Entrez ID		93661
HPRD ID		12282
Ensembl ID		ENSG00000177938
Uniprot IDs		A0A140VKF6 Q96KX2
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Localization To Bicellular Tight Junction Actin Filament-based Process Basal Body Patch Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Filament Organization Regulation Of Actin Filament-based Process Regulation Of Transepithelial Transport Actin Cytoskeleton Organization Actin Cytoskeleton Dense Body Regulation Of Supramolecular Fiber Organization Morphogenesis Of A Polarized Epithelium Structural Constituent Of Postsynaptic Actin Cytoskeleton Regulation Of Cytoskeleton Organization F-actin Capping Protein Complex Profilin Binding Postsynaptic Actin Cytoskeleton Organization Protein Localization To Cell-cell Junction Calyx Of Held Barbed-end Actin Filament Capping Postsynaptic Cytoskeleton Organization Filamentous Actin Apical Junction Complex NuA4 Histone Acetyltransferase Complex Cytoskeleton Organization Regulation Of Synaptic Vesicle Endocytosis Regulation Of Synaptic Vesicle Recycling Cortical Cytoskeleton Maintenance Of Blood-brain Barrier Actin Filament Capping Regulation Of Organelle Organization Sarcomere Organization Negative Regulation Of Actin Filament Depolymerization Myofibril Platelet Aggregation Negative Regulation Of Actin Filament Polymerization Tight Junction Assembly Regulation Of Actin Filament Depolymerization Tight Junction Organization Brush Border Homotypic Cell-cell Adhesion Positive Regulation Of Wound Healing Regulation Of Focal Adhesion Assembly Cellular Response To Type II Interferon Regulation Of Cell-substrate Junction Organization Negative Regulation Of Protein-containing Complex Disassembly Protein Localization To Cell Junction Apical Part Of Cell Actin Filament Phagocytic Vesicle
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