RAB28

Description		RAB28, member RAS oncogene family
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Plasma Membrane Endomembrane System Membrane Ciliary Rootlet Ciliary Basal Body Cell Projection
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport
Pathways
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Height ( 25282103 31562340) Obesity-related traits ( 23251661) Periodontal disease-related phenotype (Socransky) ( 24347629) Photic sneeze reflex ( 30899065)
Novel Interacting Genes		4 novel interacting genes: ACSF3 APP CC2D2A PLEKHF2
Interacting Genes		4 interacting genes: ACSF3 APP CC2D2A PLEKHF2
Entrez ID		9364
HPRD ID		06699
Ensembl ID		ENSG00000157869
Uniprot IDs		P51157
PDB IDs		2HXS 3E5H
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Malonyl-CoA Synthetase Activity Malonate Catabolic Process Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Early Endosome Membrane Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Protein Localization To Ciliary Transition Zone CoA-ligase Activity Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Early Endosome Cellular Response To Manganese Ion Very Long-chain Fatty Acid-CoA Ligase Activity Antifungal Humoral Response Nuclear Envelope Lumen Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding
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