SLC22A6

Description		solute carrier family 22 member 6
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Caveola Basal Plasma Membrane Membrane Basolateral Plasma Membrane Protein-containing Complex Extracellular Exosome
	Molecular Function	Solute:inorganic Anion Antiporter Activity Protein Binding Organic Anion Transmembrane Transporter Activity Prostaglandin Transmembrane Transporter Activity Alpha-ketoglutarate Transmembrane Transporter Activity Antiporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity Transmembrane Transporter Activity Chloride Ion Binding Identical Protein Binding Xenobiotic Transmembrane Transporter Activity
	Biological Process	Monoatomic Anion Transport Inorganic Anion Transport Organic Anion Transport Prostaglandin Transport Alpha-ketoglutarate Transport Xenobiotic Transport Sodium-independent Organic Anion Transport Transmembrane Transport Metanephric Proximal Tubule Development Renal Tubular Secretion
Pathways		Organic anion transport by SLC22 transporters
Drugs		Cefotaxime Probenecid Ceftriaxone
Diseases
GWAS		Glucose homeostasis traits ( 30576415) Urate levels ( 31578528)
Novel Interacting Genes		2 novel interacting genes: APP APPBP2
Interacting Genes		2 interacting genes: APP APPBP2
Entrez ID		9356
HPRD ID		12125
Ensembl ID		ENSG00000197901
Uniprot IDs		Q4U2R8
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Neuron Projection Maintenance RAGE Receptor Binding
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