GTF3C4

Description		general transcription factor IIIC subunit 4
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GO Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleus Nucleoplasm Mitochondrion
	Molecular Function	RNA Polymerase III General Transcription Initiation Factor Activity DNA Binding Histone Acetyltransferase Activity Protein Binding Transferase Activity Acyltransferase Activity Histone H3K14 Acetyltransferase Activity Protein-lysine-acetyltransferase Activity
	Biological Process	Chromatin Remodeling Transcription By RNA Polymerase III Transcription Initiation At RNA Polymerase III Promoter 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
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GWAS
Novel Interacting Genes		14 novel interacting genes: AURKA BRCA1 BRF1 ETS2 GTF3C1 GTF3C2 GTF3C5 H3-4 H3C15 POLR3C POLR3F PRRC2B SUMO2 TBP
Interacting Genes		14 interacting genes: AURKA BRCA1 BRF1 ETS2 GTF3C1 GTF3C2 GTF3C5 H3-4 H3C15 POLR3C POLR3F PRRC2B SUMO2 TBP
Entrez ID		9329
HPRD ID		11998
Ensembl ID		ENSG00000125484
Uniprot IDs		B3KNH2 Q9UKN8
PDB IDs		8CLI 8CLJ 8CLL
Enriched GO Terms of Interacting Partners?		Transcription By RNA Polymerase III RNA Polymerase III General Transcription Initiation Factor Activity TRNA Transcription RRNA Transcription Transcription Factor TFIIIC Complex 5S Class RRNA Transcription By RNA Polymerase III Transcription Initiation At RNA Polymerase III Promoter DNA-templated Transcription Nucleoplasm TRNA Transcription By RNA Polymerase III DNA-templated Transcription Initiation DNA Binding Nucleobase-containing Compound Biosynthetic Process Macromolecule Biosynthetic Process Protein-DNA Complex Assembly Pronucleus TRNA Metabolic Process Nucleus RRNA Metabolic Process RNA Metabolic Process Nucleic Acid Metabolic Process RNA Polymerase III Complex Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase III DNA-directed RNA Polymerase Activity Nucleobase-containing Compound Metabolic Process DNA-directed RNA Polymerase Complex Positive Regulation Of Interferon-beta Production Centrosome Cycle Condensed Nuclear Chromosome Male Germ Cell Nucleus Regulation Of Centrosome Cycle Regulation Of Interferon-beta Production Transcription Preinitiation Complex Assembly Histone H2AK127 Ubiquitin Ligase Activity Chromatin Remodeling Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Ectodermal Cell Fate Commitment Ubiquitin Protein Ligase Binding Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Microtubule Organizing Center Organization Structural Constituent Of Chromatin Transcription Factor TFIIIB Complex Protein Heterodimerization Activity Positive Regulation Of Oocyte Maturation RNA Polymerase III Type 1 Promoter Sequence-specific DNA Binding RNA Polymerase III Type 2 Promoter Sequence-specific DNA Binding Positive Regulation Of Type I Interferon Production BRCA1-B Complex
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