PTER

Description		phosphotriesterase related
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Hydrolase Activity Hydrolase Activity, Acting On Ester Bonds Metal Ion Binding N-acetyltaurine Hydrolase Activity
	Biological Process	Taurine Metabolic Process Epithelial Cell Differentiation Regulation Of Appetite
Pathways
Drugs
Diseases
GWAS		Bone fracture in osteoporosis ( 28580392) Obesity ( 19151714) Serum metabolite levels ( 33031748) Thyroid volume in Hashimoto’s thyroiditis ( 32019955) Urate levels (BMI interaction) ( 25811787)
Novel Interacting Genes		3 novel interacting genes: CACNB2 GSC2 NRP1
Interacting Genes		3 interacting genes: CACNB2 GSC2 NRP1
Entrez ID		9317
HPRD ID		16061
Ensembl ID		ENSG00000165983
Uniprot IDs		A0A0A0MSI3 Q96BW5
PDB IDs
Enriched GO Terms of Interacting Partners?		Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels Membrane Depolarization During Atrial Cardiac Muscle Cell Action Potential Positive Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Voltage-gated Calcium Channel Activity Involved In AV Node Cell Action Potential Voltage-gated Calcium Channel Activity Involved In Cardiac Muscle Cell Action Potential Otic Placode Development Ventral Trunk Neural Crest Cell Migration Vestibulocochlear Nerve Structural Organization Renal Artery Morphogenesis VEGF-activated Neuropilin Signaling Pathway Basal Dendrite Development Basal Dendrite Arborization Trigeminal Nerve Morphogenesis Angiogenesis Involved In Coronary Vascular Morphogenesis Basal Dendrite Morphogenesis Blood Vessel Endothelial Cell Fate Specification Protein Localization To Early Endosome Facioacoustic Ganglion Development Endothelial Tip Cell Fate Specification Dorsal Root Ganglion Morphogenesis Sensory Neuron Axon Guidance Trigeminal Ganglion Development Sympathetic Neuron Projection Guidance Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Endothelial Cell Fate Specification Vascular Endothelial Growth Factor Binding Neuropilin Signaling Pathway Membrane Depolarization During AV Node Cell Action Potential Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Sympathetic Neuron Projection Extension Trigeminal Nerve Structural Organization Neural Crest Cell Migration Involved In Autonomic Nervous System Development Cranial Ganglion Development Positive Regulation Of Axon Extension Involved In Axon Guidance Sorting Endosome Trunk Neural Crest Cell Migration Photoreceptor Ribbon Synapse Vascular Endothelial Growth Factor Receptor Activity Branchiomotor Neuron Axon Guidance Hepatocyte Growth Factor Receptor Signaling Pathway Hypothalamus Cell Migration L-type Voltage-gated Calcium Channel Complex Facial Nerve Structural Organization Coronary Vasculature Morphogenesis Axonogenesis Involved In Innervation Negative Regulation Of Axon Extension Involved In Axon Guidance Retina Vasculature Morphogenesis In Camera-type Eye Coronary Artery Morphogenesis Axon Extension Involved In Axon Guidance Substrate-dependent Cell Migration, Cell Extension
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