ASIC3

Description		acid sensing ion channel subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane
	Molecular Function	Monoatomic Cation Channel Activity Sodium Channel Activity Ligand-gated Sodium Channel Activity Enterobactin Transmembrane Transporter Activity PH-gated Sodium Channel Activity PH-gated Monoatomic Ion Channel Activity
	Biological Process	Monoatomic Ion Transport Monoatomic Cation Transport Sodium Ion Transport Response To Heat Response To Mechanical Stimulus Response To Acidic PH Monoatomic Ion Transmembrane Transport Sodium Ion Transmembrane Transport Enterobactin Transport Detection Of Chemical Stimulus Involved In Sensory Perception Sensory Perception Of Sour Taste Detection Of Temperature Stimulus Involved In Sensory Perception Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Detection Of Mechanical Stimulus Involved In Sensory Perception Establishment Of Localization In Cell Membrane Depolarization
Pathways		Stimuli-sensing channels
Drugs		Agmatine
Diseases
GWAS		Eyebrow thickness ( 26926045)
Novel Interacting Genes		9 novel interacting genes: ASIC2 CSNK2A1 DLG4 GOPC LIN7B MAGI1 PATJ PRKACA STOM
Interacting Genes		9 interacting genes: ASIC2 CSNK2A1 DLG4 GOPC LIN7B MAGI1 PATJ PRKACA STOM
Entrez ID		9311
HPRD ID		10626
Ensembl ID		ENSG00000213199
Uniprot IDs		A0A090N7X8 A0A090N8Q1 A0A090N8Z6 Q9UHC3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Monoatomic Ion Transmembrane Transport Plasma Membrane Postsynaptic Density Membrane Regulation Of Monoatomic Ion Transport Bicellular Tight Junction Intracellular Protein Localization Cell Junction Establishment Of Protein Localization Regulation Of Cell Junction Assembly Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Protein Localization To Synapse Regulation Of Systemic Arterial Blood Pressure By Aortic Arch Baroreceptor Feedback Cellular Component Assembly Establishment Of Localization In Cell P2Y1 Nucleotide Receptor Binding Negative Regulation Of Anion Channel Activity Regulation Of Transport Neuromuscular Junction Protein Localization To Cell Junction Synapse PH-gated Sodium Channel Activity Monoatomic Ion-gated Channel Activity Anchoring Junction Cell Periphery Protein Kinase CK2 Complex Protein Transport Symbiont-mediated Disruption Of Host Cell PML Body Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Protein Localization To Lipid Droplet Dendritic Spine Regulation Of System Process Positive Regulation Of Aggrephagy AMPA Glutamate Receptor Clustering Cell Projection Neuroligin Family Protein Binding MPP7-DLG1-LIN7 Complex Regulation Of Synapse Assembly NMDA Selective Glutamate Receptor Signaling Pathway Establishment Or Maintenance Of Cell Polarity CAMP-dependent Protein Kinase Activity
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