ATP6V1F

Description		ATPase H+ transporting V1 subunit F
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GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Plasma Membrane Endosome Membrane Membrane Vacuolar Proton-transporting V-type ATPase Complex Clathrin-coated Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Proton-transporting V-type ATPase, V1 Domain Synapse Extracellular Exosome
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity ATPase-coupled Ion Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Monoatomic Ion Transport Vacuolar Acidification Lysosomal Lumen Acidification Monoatomic Ion Transmembrane Transport Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS		Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Novel Interacting Genes		1 novel interacting genes: CEP126
Interacting Genes		1 interacting genes: CEP126
Entrez ID		9296
HPRD ID		06198
Ensembl ID		ENSG00000128524
Uniprot IDs		A4D1K0 Q16864
PDB IDs		6WLZ 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?		Non-motile Cilium Assembly Cytoplasmic Microtubule Organization Ciliary Base Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis Midbody Spindle Organization
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