ARRDC1

Description		arrestin domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Cytoplasmic Vesicle Extracellular Exosome Extracellular Vesicle
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity Arrestin Family Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Extracellular Transport Protein Transport Protein Ubiquitination Negative Regulation Of Notch Signaling Pathway Extracellular Vesicle Biogenesis
Pathways
Drugs
Diseases
GWAS		Asthma ( 32296059) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433)
Novel Interacting Genes		8 novel interacting genes: APP DAPK1 EPN2 FAM13A-AS1 MTDH MTURN PDCD6IP UBASH3A
Interacting Genes		8 interacting genes: APP DAPK1 EPN2 FAM13A-AS1 MTDH MTURN PDCD6IP UBASH3A
Entrez ID		92714
HPRD ID		12491
Ensembl ID		ENSG00000197070
Uniprot IDs		Q8N5I2
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Regulation Of Signal Transduction Amylin Binding Positive Regulation Of JNK Cascade Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Communication Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Signaling Regulation Of NMDA Receptor Activity DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Extracellular Vesicle Biogenesis Extracellular Exosome Biogenesis Positive Regulation Of Extracellular Exosome Assembly Bicellular Tight Junction Proteinase Activated Receptor Binding Actomyosin Contractile Ring Assembly Intermediate-density Lipoprotein Particle Regulation Of JNK Cascade Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Positive Regulation Of Autophagy Regulation Of Extracellular Exosome Assembly Intercellular Canaliculus
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