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MGME1

Description mitochondrial genome maintenance exonuclease 1
Image
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Matrix
Molecular Function
  • Nuclease Activity
  • Exonuclease Activity
  • Protein Binding
  • Single-stranded DNA Exodeoxyribonuclease Activity
  • Hydrolase Activity
  • 5'-flap Endonuclease Activity
  • Single-stranded DNA 5'-3' DNA Exonuclease Activity
Biological Process
  • Mitochondrial DNA Replication
  • DNA Repair
  • DNA Damage Response
  • Mitochondrial DNA Repair
Pathways
  • Strand-asynchronous mitochondrial DNA replication
Drugs
Diseases
GWAS
Novel Interacting Genes 2 novel interacting genes: MAGEA11 PICK1
Interacting Genes 2 interacting genes: MAGEA11 PICK1
Entrez ID 92667
HPRD ID 12783
Ensembl ID ENSG00000125871
Uniprot IDs Q5QPE7 Q5QPE8 Q9BQP7
PDB IDs 5ZYT 5ZYU 5ZYV 5ZYW 8XA9
Enriched GO Terms of Interacting Partners?
  • Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation
  • Membrane Curvature Sensor Activity
  • Negative Regulation Of Actin Nucleation
  • Neuronal Ion Channel Clustering
  • Dendritic Spine Maintenance
  • Arp2/3 Complex Binding
  • Long-term Synaptic Depression
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