G6PC3

Description		glucose-6-phosphatase catalytic subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Glucose-6-phosphatase Activity Hydrolase Activity
	Biological Process	Gluconeogenesis Glucose-6-phosphate Transport Glucose 6-phosphate Metabolic Process
Pathways		Severe congenital neutropenia type 4 (G6PC3) Gluconeogenesis
Drugs
Diseases		Neutropenia, severe congenital 4, autosomal recessive; G6PC3 deficiency; Darsun syndrome
GWAS		Bipolar disorder ( 31043756) Glycated hemoglobin levels ( 24244560) Height ( 33713608)
Novel Interacting Genes		4 novel interacting genes: CCR9 CNKSR1 GPR37 HTR2B
Interacting Genes		4 interacting genes: CCR9 CNKSR1 GPR37 HTR2B
Entrez ID		92579
HPRD ID		13556
Ensembl ID		ENSG00000141349
Uniprot IDs		A0A8Q3SIG5 K7EJC5 Q9BUM1
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Prosaposin Receptor Activity Gq/11-coupled Serotonin Receptor Activity Positive Regulation Of Phosphatidylinositol Biosynthetic Process Calcium-mediated Signaling CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation G Protein-coupled Serotonin Receptor Complex Intestine Smooth Muscle Contraction Positive Regulation Of Dopamine Metabolic Process Locomotion Involved In Locomotory Behavior Phospholipase C-activating Serotonin Receptor Signaling Pathway Locomotion Dopamine Biosynthetic Process Serotonin Binding Positive Regulation Of Phospholipid Biosynthetic Process Serotonin Receptor Signaling Pathway Gamma-delta T Cell Differentiation Serotonin Receptor Activity Neural Crest Cell Differentiation G Protein-coupled Serotonin Receptor Activity Regulation Of Dopamine Metabolic Process Signal Transduction Catecholamine Biosynthetic Process Positive Regulation Of MAPK Cascade Dendrite Neuropeptide Receptor Activity Plasma Membrane Regulation Of Phospholipid Biosynthetic Process Neurotransmitter Receptor Activity G Protein-coupled Serotonin Receptor Signaling Pathway Gamma-delta T Cell Activation Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Cardiac Muscle Hypertrophy Neuropeptide Binding Muscle Hypertrophy Peptide Binding G-protein Alpha-subunit Binding CGMP-mediated Signaling Dopamine Metabolic Process Vasoconstriction Amine Biosynthetic Process Biogenic Amine Biosynthetic Process Regulation Of MAPK Cascade Cell Surface Regulation Of Phospholipid Metabolic Process G Protein-coupled Peptide Receptor Activity Dendrite Development
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