KCNAB3

Description		potassium voltage-gated channel subfamily A regulatory beta subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex
	Molecular Function	Voltage-gated Potassium Channel Activity Protein Binding Alcohol Dehydrogenase (NADP+) Activity Potassium Channel Regulator Activity Oxidoreductase Activity Transmembrane Transporter Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels
Drugs
Diseases
GWAS		Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Refractive error ( 32231278) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Novel Interacting Genes		5 novel interacting genes: APP GMDS NEDD4L PLEKHF2 ZBTB14
Interacting Genes		5 interacting genes: APP GMDS NEDD4L PLEKHF2 ZBTB14
Entrez ID		9196
HPRD ID		04983
Ensembl ID		ENSG00000170049
Uniprot IDs		O43448
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Early Endosome Membrane Axon Midline Choice Point Recognition Endosome Amylin Binding Positive Regulation Of Protein Catabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Endocytosis Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Notch Signaling Pathway Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling GDP-mannose 4,6-dehydratase Activity NADP+ Binding GDP-L-fucose Biosynthetic Process 'de Novo' GDP-L-fucose Biosynthetic Process Negative Regulation Of Sodium Ion Import Across Plasma Membrane Positive Regulation Of Caveolin-mediated Endocytosis Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Negative Regulation Of Protein Localization Regulation Of Toll Signaling Pathway GDP-L-fucose Metabolic Process Negative Regulation Of Potassium Ion Export Across Plasma Membrane Axon Choice Point Recognition Regulation Of Caveolin-mediated Endocytosis Synapse Organization Heparan Sulfate Binding Signaling Receptor Activator Activity
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