FIBP

Description		FGF1 intracellular binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Endomembrane System Membrane Nuclear Speck
	Molecular Function	Fibroblast Growth Factor Binding
	Biological Process	Fibroblast Growth Factor Receptor Signaling Pathway Platelet Aggregation
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Asthma ( 31959851) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Psoriasis ( 28537254)
Novel Interacting Genes		10 novel interacting genes: APP CSNK2A1 CSNK2B DAPK1 FGF1 FGFBP1 GSK3B PKNOX1 RNF32 TENM1
Interacting Genes		10 interacting genes: APP CSNK2A1 CSNK2B DAPK1 FGF1 FGFBP1 GSK3B PKNOX1 RNF32 TENM1
Entrez ID		9158
HPRD ID		08492
Ensembl ID		ENSG00000172500
Uniprot IDs		O43427
PDB IDs
Enriched GO Terms of Interacting Partners?		Heparin Binding Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Cell Surface Receptor Signaling Pathway Regulation Of Signal Transduction Regulation Of Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Proteolysis Regulation Of Translation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Protein Serine/threonine Kinase Activity Regulation Of Cell Communication Regulation Of Signaling Regulation Of Cell Migration Regulation Of Cell Population Proliferation PcG Protein Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Autophagy Regulation Of Cell Motility Regulation Of Endothelial Cell Migration Regulation Of Locomotion Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Catabolic Process Positive Regulation Of Cell Migration Positive Regulation Of MAP Kinase Activity Positive Regulation Of Protein Catabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Motility Negative Regulation Of Protein Metabolic Process Neuron Projection Organization Post-transcriptional Regulation Of Gene Expression Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Locomotion Negative Regulation Of Protein Localization To Nucleus Regulation Of Intracellular Signal Transduction Positive Regulation Of Protein Transport Cellular Response To Amyloid-beta Signal Transduction Wnt Signaling Pathway Negative Regulation Of Cell Population Proliferation
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