SESTD1

Description		SEC14 and spectrin domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Calcium Channel Complex Intermediate Filament Cytoskeleton
	Molecular Function	Phosphatidylserine Binding Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylcholine Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Negative Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel
Pathways
Drugs
Diseases
GWAS		Late-onset Alzheimer's disease ( 27770636) Objective response to lithium treatment ( 26503763) Optic disc size ( 31809533) Presence of antiphospholipid antibodies ( 23509613) Refractive error ( 32231278) Serum uric acid levels ( 29559957)
Novel Interacting Genes		10 novel interacting genes: CBX8 GPS2 HSF4 IQCB1 NRIP1 RABGEF1 STMN1 STMN2 TEAD4 ZNF830
Interacting Genes		10 interacting genes: CBX8 GPS2 HSF4 IQCB1 NRIP1 RABGEF1 STMN1 STMN2 TEAD4 ZNF830
Entrez ID		91404
HPRD ID		11549
Ensembl ID		ENSG00000187231
Uniprot IDs		B3KTX3 Q86VW0
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Microtubule Polymerization Microtubule Depolymerization Microtubule Polymerization Or Depolymerization Protein Depolymerization Ovulation Cycle Process Negative Regulation Of Microtubule Polymerization Or Depolymerization Tubulin Binding Negative Regulation Of Small GTPase Mediated Signal Transduction Trophectodermal Cell Fate Commitment Ovarian Follicle Rupture Regulation Of Microtubule Polymerization BBSome Binding Negative Regulation Of Kit Signaling Pathway Negative Regulation Of Mast Cell Cytokine Production Preantral Ovarian Follicle Growth Negative Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Response To Cytokine Stimulus Negative Regulation Of Transcription By RNA Polymerase II Nuclear Speck Regulation Of Microtubule Polymerization Or Depolymerization Kit Signaling Pathway Intracellular Signal Transduction Transcription Coregulator Activity Chromatin Maintenance Of Animal Organ Identity Negative Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Microtubule Depolymerization
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