INA

Description		internexin neuronal intermediate filament protein alpha
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Intermediate Filament Neurofilament Cytoplasmic Ribonucleoprotein Granule Intermediate Filament Cytoskeleton Schaffer Collateral - CA1 Synapse Postsynapse Postsynaptic Intermediate Filament Cytoskeleton
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Postsynaptic Intermediate Filament Cytoskeleton
	Biological Process	Nervous System Development Substantia Nigra Development Cell Differentiation Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization Neurofilament Cytoskeleton Organization Postsynaptic Modulation Of Chemical Synaptic Transmission Postsynaptic Intermediate Filament Cytoskeleton Organization Cellular Response To Leukemia Inhibitory Factor
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Estimated glomerular filtration rate in non-diabetics ( 31451708) Migraine ( 22683712) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 23974872 25056061 28991256 29483656)
Novel Interacting Genes		5 novel interacting genes: FXR1 GRIN1 GRIN2D STAU1 TANC1
Interacting Genes		5 interacting genes: FXR1 GRIN1 GRIN2D STAU1 TANC1
Entrez ID		9118
HPRD ID		05628
Ensembl ID		ENSG00000148798
Uniprot IDs		Q16352
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Synaptic Plasticity Regulation Of Neuronal Synaptic Plasticity Regulation Of Synaptic Transmission, Glutamatergic NMDA Glutamate Receptor Activity Glutamate Binding NMDA Selective Glutamate Receptor Complex Excitatory Chemical Synaptic Transmission Glutamate-gated Calcium Ion Channel Activity Dendrite Modulation Of Chemical Synaptic Transmission Positive Regulation Of Synaptic Transmission Glutamatergic Synapse Positive Regulation Of Excitatory Postsynaptic Potential Ligand-gated Monoatomic Ion Channel Activity Positive Regulation Of Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Synapse Ligand-gated Ion Channel Signaling Pathway Regulation Of Long-term Synaptic Potentiation Neuron Projection Modulation Of Excitatory Postsynaptic Potential Glutamate Receptor Signaling Pathway Visual Learning Visual Behavior Excitatory Postsynaptic Potential Cytoplasmic Ribonucleoprotein Granule Calcium Ion Transmembrane Import Into Cytosol Propylene Metabolic Process Cytoplasmic Stress Granule Associative Learning Regulation Of Postsynaptic Membrane Potential Postsynaptic Density Membrane Response To Amino Acid Regulation Of Nervous System Process Response To Glycine Positive Regulation Of Cell Communication Positive Regulation Of Signaling Dendritic Spine Glycine-gated Cation Channel Activity Learning Anterograde Dendritic Transport Of Messenger Ribonucleoprotein Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Monoatomic Ion Channel Activity Calcium-mediated Signaling Positive Regulation By Virus Of Viral Protein Levels In Host Cell Nervous System Process Calcium Ion Transmembrane Transport Germ Cell Development LncRNA-mediated Post-transcriptional Gene Silencing RNA Strand Annealing Activity
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