DPP9

Description		dipeptidyl peptidase 9
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Microtubule Cell Leading Edge
	Molecular Function	Aminopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Dipeptidyl-peptidase Activity Hydrolase Activity Identical Protein Binding
	Biological Process	Proteolysis Negative Regulation Of Programmed Cell Death Protein Maturation Pyroptotic Inflammatory Response CARD8 Inflammasome Complex Assembly Pyroptotic Cell Death NLRP1 Inflammasome Complex Assembly
Pathways
Drugs
Diseases
GWAS		Idiopathic pulmonary fibrosis ( 31710517) Interstitial lung disease ( 23583980) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485)
Novel Interacting Genes		2 novel interacting genes: HRAS SYK
Interacting Genes		2 interacting genes: HRAS SYK
Entrez ID		91039
HPRD ID		07001
Ensembl ID		ENSG00000142002
Uniprot IDs		M0R2A8 Q86TI2
PDB IDs		6EOQ 6EOR 6QZV 6X6A 6X6C 7A3F 7JKQ 7JN7 7SVL 7SVN 7ZXS
Enriched GO Terms of Interacting Partners?		Locomotion Phospholipase C Activator Activity Regulation Of ERK1 And ERK2 Cascade Antigen Receptor-mediated Signaling Pathway Adaptive Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Apoptotic Signaling Pathway Immune Response-activating Signaling Pathway Chemotaxis GTPase Complex Beta Selection Interleukin-15 Receptor Binding Serotonin Secretion Cellular Response To Molecule Of Fungal Origin Positive Regulation Of Interleukin-3 Production B Cell Receptor Complex Serotonin Secretion By Platelet Immune Response-regulating Signaling Pathway Endocytosis Positive Regulation Of MAPK Cascade Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Activation Of Immune Response Regulation Of Arachidonate Secretion Positive Regulation Of Mast Cell Cytokine Production Toll-like Receptor Binding Response To Molecule Of Fungal Origin Oncogene-induced Cell Senescence Regulation Of Neutrophil Degranulation Interleukin-3-mediated Signaling Pathway Positive Regulation Of Cytokine Production Positive Regulation Of Cellular Component Biogenesis Animal Organ Morphogenesis Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Immune Response Enzyme-linked Receptor Protein Signaling Pathway Import Into Cell T-helper 1 Type Immune Response Regulation Of MAPK Cascade Positive Regulation Of Gamma-delta T Cell Activation Positive Regulation Of Bone Resorption Early Phagosome Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Gamma-delta T Cell Differentiation Serotonin Transport Lymph Vessel Development Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Neutrophil Activation Involved In Immune Response Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Ruffle Assembly
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