CD1A

Description		CD1a molecule
Image
GO Annotations	Cellular Component	Extracellular Space Endosome Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Membrane Membrane Raft
	Molecular Function	Protein Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Adaptive Immune Response Immune System Process Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Antithymocyte immunoglobulin (rabbit)
Diseases
GWAS		Change in neurofilament light levels ( 31295725) Dental caries (decayed and filled deciduous teeth) ( 31533690)
Novel Interacting Genes		4 novel interacting genes: B2M DGAT1 KCTD5 UBTD1
Interacting Genes		4 interacting genes: B2M DGAT1 KCTD5 UBTD1
Entrez ID		909
HPRD ID		01776
Ensembl ID		ENSG00000158477
Uniprot IDs		P06126
PDB IDs		1ONQ 1XZ0 4X6C 4X6D 4X6E 4X6F 5J1A 6NUX 7KOZ 7KP0 7KP1 7RYM 7RYN 7RYO 7SH4
Enriched GO Terms of Interacting Partners?		Cellular Response To Iron(III) Ion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class Ib Protein Homooligomerization Negative Regulation Of Forebrain Neuron Differentiation Regulation Of Forebrain Neuron Differentiation Response To Iron(III) Ion Antigen Processing And Presentation Of Exogenous Protein Antigen Via MHC Class Ib, TAP-dependent Negative Regulation Of Iron Ion Transport Diacylglycerol O-acyltransferase Activity 2-acylglycerol O-acyltransferase Activity Retinol O-fatty-acyltransferase Activity Cellular Response To Nicotine HFE-transferrin Receptor Complex Regulation Of Iron Ion Transport MHC Class I Protein Complex MHC Class I Peptide Loading Complex Cellular Response To Iron Ion Early Endosome Lumen Protein Complex Oligomerization Protein-containing Complex Organization Peptide Antigen Assembly With MHC Class I Protein Complex Protein-containing Complex Assembly Monoacylglycerol Biosynthetic Process Transferrin Transport Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Cellular Senescence Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Identical Protein Binding Fatty Acid Homeostasis Triglyceride Biosynthetic Process MHC Class II Protein Complex Binding T Cell Mediated Cytotoxicity Multicellular Organismal-level Iron Ion Homeostasis Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Long-chain Fatty-acyl-CoA Metabolic Process Diacylglycerol Metabolic Process O-acyltransferase Activity Protein-lipid Complex Assembly Plasma Lipoprotein Particle Assembly Cullin Family Protein Binding Protein Refolding Positive Regulation Of T Cell Cytokine Production Antigen Processing And Presentation Of Endogenous Antigen Amyloid Fibril Formation Positive Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Response To Iron Ion Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
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