DIRAS3

Description		DIRAS family GTPase 3
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GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Signal Transduction Small GTPase-mediated Signal Transduction Genomic Imprinting
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes		14 novel interacting genes: ACADM APC BAG4 BRMS1 CHEK2 FGFR4 HTR2A KRAS MEOX2 PALB2 PPM1D PTPN1 TGFB1 WT1
Interacting Genes		14 interacting genes: ACADM APC BAG4 BRMS1 CHEK2 FGFR4 HTR2A KRAS MEOX2 PALB2 PPM1D PTPN1 TGFB1 WT1
Entrez ID		9077
HPRD ID		05547
Ensembl ID		ENSG00000162595
Uniprot IDs		O95661
PDB IDs		6NAZ
Enriched GO Terms of Interacting Partners?		Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Protein-containing Complex Binding Regulation Of Primary Metabolic Process Regulation Of Metabolic Process Regulation Of Signal Transduction Regulation Of Cell Population Proliferation Positive Regulation Of Anoikis Positive Regulation Of Macromolecule Metabolic Process Response To Nutrient Levels Positive Regulation Of Metabolic Process Regulation Of Cell Communication Regulation Of Macromolecule Metabolic Process Regulation Of Signaling Regulation Of Intracellular Signal Transduction Gland Development Regulation Of Cell Migration Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Fibroblast Migration Liver Development Regulation Of Protein Metabolic Process Regulation Of Cell Motility Regulation Of Locomotion Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Intracellular Signal Transduction Branching Morphogenesis Of An Epithelial Tube Positive Regulation Of Endothelial Cell Apoptotic Process Negative Regulation Of Locomotion Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Cell Population Proliferation Regulation Of Anoikis Morphogenesis Of A Branching Epithelium Pattern Specification Process Tissue Morphogenesis Morphogenesis Of A Branching Structure Negative Regulation Of Protein Serine/threonine Kinase Activity Response To Radiation Phosphate-containing Compound Metabolic Process Positive Regulation Of MAPK Cascade Positive Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Apoptotic Process Regulation Of Kidney Development Apoptotic Process Regulation Of Fibroblast Migration Ureteric Bud Development Negative Regulation Of Programmed Cell Death
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