LIMD1

Description		LIM domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Plasma Membrane Adherens Junction Focal Adhesion RISC Complex Anchoring Junction
	Molecular Function	Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Response To Hypoxia Osteoblast Development Regulation Of DNA-templated Transcription Cytoskeleton Organization Regulation Of Cell Shape Phosphorylation Cell Migration Regulatory NcRNA-mediated Gene Silencing P-body Assembly MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Hippo Signaling Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Macular telangiectasia type 2 ( 33654266) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 30578418)
Novel Interacting Genes		7 novel interacting genes: APP BRCA2 HIPK3 NGLY1 RPP14 STAC TRAF6
Interacting Genes		7 interacting genes: APP BRCA2 HIPK3 NGLY1 RPP14 STAC TRAF6
Entrez ID		8994
HPRD ID		05177
Ensembl ID		ENSG00000144791
Uniprot IDs		Q9UGP4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of JNK Cascade Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Response To Interleukin-1 Regulation Of Phosphorus Metabolic Process Growth Cone Lamellipodium Positive Regulation Of Mitotic Cell Cycle Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Positive Regulation Of Interleukin-6 Production Amylin Binding Positive Regulation Of JNK Cascade Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Myeloid Leukocyte Activation Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Mitotic Recombination-dependent Replication Fork Processing BRCA2-MAGE-D1 Complex Cytoplasmic Side Of Plasma Membrane Regulation Of MAP Kinase Activity MRNA Transcription Regulation Of Protein Serine/threonine Kinase Activity Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cell Maturation Regulation Of Interleukin-6 Production Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Regulation Of MAPK Cascade Low-density Lipoprotein Particle Mediated Signaling Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Protein Localization To Membrane Positive Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Protein Localization To Cell Periphery Endoribonuclease Complex Ribonuclease P Complex
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