ATG16L2

Description		autophagy related 16 like 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Autophagosome Cytosol Phagophore Assembly Site Membrane Atg12-Atg5-Atg16 Complex
	Molecular Function
	Biological Process	Autophagosome Assembly Autophagy Protein Transport Macroautophagy Negative Stranded Viral RNA Replication
Pathways		Macroautophagy
Drugs
Diseases
GWAS		Crohn's disease ( 23266558 23850713) Non-albumin protein levels ( 29403010) Systemic lupus erythematosus ( 26663301)
Novel Interacting Genes		4 novel interacting genes: ATG5 RAB33A RAB33B TK1
Interacting Genes		4 interacting genes: ATG5 RAB33A RAB33B TK1
Entrez ID		89849
HPRD ID		10959
Ensembl ID		ENSG00000168010
Uniprot IDs		Q8NAA4
PDB IDs
Enriched GO Terms of Interacting Partners?		Autophagosome Organization Autophagosome Assembly Rab Protein Signal Transduction Vacuole Organization Phagophore Assembly Site Membrane Cellular Component Assembly Thymidine Kinase Activity Organelle Assembly Antigen Processing And Presentation Otolith Development Positive Regulation Of Viral Translation Negative Regulation Of Constitutive Secretory Pathway Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER DNA Synthesis Involved In Mitotic DNA Replication Negative Regulation Of Autophagic Cell Death Phagophore Atg8-family Ligase Activity Negative Stranded Viral RNA Replication Response To Fluoride Cellular Response To Nitrosative Stress Thymidine Biosynthetic Process Positive Regulation Of Mucus Secretion Thymidine Metabolic Process Small GTPase-mediated Signal Transduction Positive Regulation Of Stress Granule Assembly Chaperone-mediated Autophagy Response To Iron(II) Ion Viral RNA Genome Replication Atg12-Atg5-Atg16 Complex Autophagy Regulation Of Mucus Secretion Response To Nitrosative Stress GTPase Activity Deoxyribonucleoside Monophosphate Biosynthetic Process Ventricular Cardiac Muscle Cell Development Cellular Response To Nitrogen Starvation GTP Binding Regulation Of Stress Granule Assembly Pyrimidine Nucleoside Metabolic Process Cardiac Muscle Cell Apoptotic Process Negative Thymic T Cell Selection Negative T Cell Selection Transferase Complex Aggrephagy Striated Muscle Cell Apoptotic Process Regulation Of Autophagosome Maturation Mucus Secretion Negative Regulation Of Transport Nucleotide Binding Negative Regulation Of Defense Response To Virus
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