ANKRD13A

Description		ankyrin repeat domain 13A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Late Endosome Plasma Membrane Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Ubiquitin-modified Protein Reader Activity
	Biological Process	Negative Regulation Of Receptor Internalization Negative Regulation Of Protein Localization To Endosome
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Metabolite levels (MHPG) ( 23319000) Systolic blood pressure ( 30578418)
Novel Interacting Genes		12 novel interacting genes: FBXO25 GRB2 LAPTM5 MFHAS1 QDPR RIPK1 RNF11 SMAD5 SMURF1 UBC VCP WBP2
Interacting Genes		12 interacting genes: FBXO25 GRB2 LAPTM5 MFHAS1 QDPR RIPK1 RNF11 SMAD5 SMURF1 UBC VCP WBP2
Entrez ID		88455
HPRD ID		12458
Ensembl ID		ENSG00000076513
Uniprot IDs		Q3ZTS7 Q8IZ07 Q9Y5A3
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Binding Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Intracellular Signal Transduction I-SMAD Binding Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Signal Transduction Post-translational Protein Modification Vacuolar Transport Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Ubiquitin-dependent Protein Catabolic Process Guanyl-nucleotide Exchange Factor Adaptor Activity Regulation Of Cell Communication Cytoplasm Regulation Of Signaling Mitochondrion Dihydrobiopterin Metabolic Process 6,7-dihydropteridine Reductase Activity Protein Modification Process Macromolecule Catabolic Process Modification-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Flavin Adenine Dinucleotide Catabolic Process Positive Regulation Of Intracellular Signal Transduction Induction Of Programmed Cell Death Negative Regulation Of Pre-B Cell Receptor Expression Positive Regulation Of Lysosomal Membrane Permeability Protein Targeting To Vacuole Engulfment Of Target By Autophagosome Canonical NF-kappaB Signal Transduction Regulation Of MAPK Cascade Establishment Of Protein Localization To Vacuole Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Reactive Oxygen Species Metabolic Process Proteolysis Involved In Protein Catabolic Process Catabolic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Regulation Of Intracellular Signal Transduction Grb2-EGFR Complex Negative Regulation Of Fas Signaling Pathway Erythrocyte Differentiation VCP-NSFL1C Complex Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control
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