MTMR1

Description		myotubularin related protein 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Phosphatidylinositol-3-phosphate Phosphatase Activity Hydrolase Activity Protein Homodimerization Activity Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity Phosphatidylinositol Phosphate Phosphatase Activity
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Protein Destabilization Phosphatidylinositol Dephosphorylation Regulation Of Phosphatidylinositol Dephosphorylation
Pathways		Synthesis of PIPs at the plasma membrane RHOF GTPase cycle
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494)
Novel Interacting Genes		3 novel interacting genes: ERBB3 PTK7 ROR2
Interacting Genes		3 interacting genes: ERBB3 PTK7 ROR2
Entrez ID		8776
HPRD ID		02163
Ensembl ID		ENSG00000063601
Uniprot IDs		B7Z3D5 E9PPP8 F8WA39 Q13613 Q8NEC6
PDB IDs		5C16
Enriched GO Terms of Interacting Partners?		Mesenchyme Development Protein Kinase Activity Coreceptor Activity Wound Healing Protein Tyrosine Kinase Activity Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Receptor Complex Response To Wounding ATP Binding Neuregulin Receptor Activity Heart Development ErbB-3 Class Receptor Binding Neuregulin Binding Regulation Of Cardiac Muscle Tissue Development Wnt Signaling Pathway Schwann Cell Differentiation ERBB2-ERBB3 Signaling Pathway Cell Surface Receptor Signaling Pathway ERBB3 Signaling Pathway Axon Lung-associated Mesenchyme Development Negative Regulation Of Motor Neuron Apoptotic Process Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Receptor Activity Endocardial Cushion Development Convergent Extension Positive Regulation Of Striated Muscle Tissue Development Regulation Of Motor Neuron Apoptotic Process Enzyme-linked Receptor Protein Signaling Pathway Kinase Activity Schwann Cell Development Motor Neuron Apoptotic Process ERBB2 Signaling Pathway Protein Tyrosine Kinase Activator Activity Positive Regulation Of Calcineurin-NFAT Signaling Cascade Mitogen-activated Protein Kinase Kinase Kinase Binding Establishment Of Planar Polarity Establishment Of Apical/basal Cell Polarity Axis Elongation Establishment Of Monopolar Cell Polarity Establishment Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Polarized Epithelial Cell Differentiation Peripheral Nervous System Development Coronary Vasculature Development Cochlea Morphogenesis Wnt-protein Binding Tissue Development Establishment Of Epithelial Cell Polarity
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