DGAT1

Description		diacylglycerol O-acyltransferase 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	2-acylglycerol O-acyltransferase Activity Diacylglycerol O-acyltransferase Activity Protein Binding O-acyltransferase Activity Transferase Activity Acyltransferase Activity Identical Protein Binding Retinol O-fatty-acyltransferase Activity
	Biological Process	Retinoid Metabolic Process Lipid Metabolic Process Monoacylglycerol Biosynthetic Process Triglyceride Metabolic Process Triglyceride Biosynthetic Process Lipid Storage Very-low-density Lipoprotein Particle Assembly Long-chain Fatty-acyl-CoA Metabolic Process Retinol Metabolic Process Diacylglycerol Metabolic Process Glycerolipid Metabolic Process Fatty Acid Homeostasis
Pathways		Acyl chain remodeling of DAG and TAG Neutrophil degranulation Triglyceride biosynthesis
Drugs
Diseases
GWAS		Dupuytren's disease ( 28886342) Fasting glucose ( 34059833)
Novel Interacting Genes		4 novel interacting genes: CCR9 CD1A GABRA4 GPAA1
Interacting Genes		4 interacting genes: CCR9 CD1A GABRA4 GPAA1
Entrez ID		8694
HPRD ID		05360
Ensembl ID		ENSG00000185000
Uniprot IDs		O75907
PDB IDs		6VP0 6VYI 6VZ1 8ESM 8ETM
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Exogenous Lipid Antigen Binding Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Endogenous Lipid Antigen Binding GPI-anchor Transamidase Activity GPI-anchor Transamidase Complex Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Protein Retention In ER Lumen Lipopeptide Binding GPI Anchor Binding External Side Of Plasma Membrane Benzodiazepine Receptor Activity Gamma-delta T Cell Differentiation Maintenance Of Protein Localization In Endoplasmic Reticulum GABA-A Receptor Activity GABA-A Receptor Complex GABA-gated Chloride Ion Channel Activity Inhibitory Synapse Assembly Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Gamma-delta T Cell Activation Antigen Processing And Presentation Of Endogenous Antigen Gamma-aminobutyric Acid Signaling Pathway Postsynaptic Specialization Membrane GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Dendrite Membrane Synaptic Transmission, GABAergic Positive Regulation Of T Cell Mediated Cytotoxicity Extracellular Ligand-gated Monoatomic Ion Channel Activity Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
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