DENR

Description		density regulated re-initiation and release factor
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GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Translation Initiation Factor Activity Protein Binding
	Biological Process	Formation Of Translation Preinitiation Complex Cytoplasmic Translational Initiation Translation Reinitiation Translation Translational Initiation Ribosome Disassembly IRES-dependent Viral Translational Initiation
Pathways
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Thrombin-activatable fibrinolysis inhibitor levels ( 29378355)
Novel Interacting Genes		4 novel interacting genes: MCTS1 NELFB SCARB1 UBC
Interacting Genes		4 interacting genes: MCTS1 NELFB SCARB1 UBC
Entrez ID		8562
HPRD ID		05182
Ensembl ID		ENSG00000139726
Uniprot IDs		O43583
PDB IDs		5ONS 5VYC 6MS4 6VPQ 6VPR
Enriched GO Terms of Interacting Partners?		Endocytic Vesicle Membrane Positive Regulation Of Sphingolipid Mediated Signaling Pathway High-density Lipoprotein Particle Receptor Activity High Density Lipoprotein Particle Mediated Signaling Regulation Of Sphingolipid Mediated Signaling Pathway Lipopolysaccharide Transport Cholesterol Catabolic Process Recognition Of Apoptotic Cell Lipopolysaccharide Immune Receptor Activity Positive Regulation Of Cholesterol Storage Positive Regulation Of Nitric Oxide Mediated Signal Transduction Cholesterol Import Detection Of Lipopolysaccharide Regulation Of Phospholipid Catabolic Process Apolipoprotein A-I Binding High-density Lipoprotein Particle Clearance Regulation Of Phosphatidylcholine Catabolic Process NELF Complex Translation Reinitiation Formation Of Translation Preinitiation Complex Detection Of Molecule Of Bacterial Origin Regulation Of Phosphatidylcholine Metabolic Process Positive Regulation Of Triglyceride Biosynthetic Process Regulation Of Nitric Oxide Mediated Signal Transduction High-density Lipoprotein Particle Binding Intestinal Lipid Absorption Phagocytosis, Recognition RNA Binding RNA Cap Binding IRES-dependent Viral Translational Initiation Adhesion Of Symbiont To Host 1-phosphatidylinositol Binding Low-density Lipoprotein Particle Binding Apolipoprotein Binding Low-density Lipoprotein Particle Clearance Reverse Cholesterol Transport Vitamin Transmembrane Transport Protein Tag Activity Regulation Of Triglyceride Biosynthetic Process High-density Lipoprotein Particle Remodeling Ribosomal Small Subunit Binding Positive Regulation Of Lipid Storage Positive Regulation Of Triglyceride Metabolic Process Steroid Catabolic Process Negative Regulation Of Transcription Elongation By RNA Polymerase II Scavenger Receptor Activity Negative Regulation Of Stem Cell Differentiation Negative Regulation Of DNA-templated Transcription, Elongation Plasma Lipoprotein Particle Clearance Intestinal Absorption
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