ITPRIP

Description		inositol 1,4,5-trisphosphate receptor interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Outer Membrane Plasma Membrane Membrane
	Molecular Function	Protein Kinase Inhibitor Activity Protein Binding
	Biological Process	Signal Transduction Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Signal Transduction Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494)
Novel Interacting Genes		5 novel interacting genes: ITPR1 NLGN3 PGRMC2 RASSF3 SGTB
Interacting Genes		5 interacting genes: ITPR1 NLGN3 PGRMC2 RASSF3 SGTB
Entrez ID		85450
HPRD ID		13892
Ensembl ID		ENSG00000148841
Uniprot IDs		Q8IWB1
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellularly Gated Calcium Channel Activity Platelet Dense Tubular Network Protein Homooligomerization Inositol 1,4,5-trisphosphate-gated Calcium Channel Activity Inositol 1,4,5-trisphosphate Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Levels Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Epithelial Fluid Transport Platelet Dense Granule Membrane Nuclear Envelope Protein Complex Oligomerization Calcium Ion Transmembrane Transporter Activity Platelet Dense Tubular Network Membrane Synapse Calcium Import Into The Mitochondrion Calcineurin Complex Voluntary Musculoskeletal Movement Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Inositol 1,4,5 Trisphosphate Binding Heme Transmembrane Transporter Activity Heme Transport Neurexin Family Protein Binding Asymmetric, Glutamatergic, Excitatory Synapse Regulation Of Respiratory Gaseous Exchange By Nervous System Process Inhibitory Postsynaptic Potential Positive Regulation Of Glutamate Receptor Signaling Pathway Rhythmic Synaptic Transmission Postsynaptic Membrane Assembly Postsynaptic Membrane Organization Presynaptic Membrane Assembly Regulation Of Glutamate Receptor Signaling Pathway Symmetric, GABA-ergic, Inhibitory Synapse Neuron To Neuron Synapse Presynapse Assembly Presynaptic Membrane Organization Post-translational Protein Targeting To Endoplasmic Reticulum Membrane TRC Complex Musculoskeletal Movement Calcium Channel Inhibitor Activity Regulation Of Respiratory System Process Neuron Cell-cell Adhesion Mitochondrial Calcium Ion Transmembrane Transport Presynapse Organization G Protein-coupled Acetylcholine Receptor Signaling Pathway Negative Regulation Of Calcium-mediated Signaling Vocalization Behavior Nuclear Steroid Receptor Activity Regulation Of Respiratory Gaseous Exchange Endoplasmic Reticulum Calcium Ion Homeostasis Protein Heterooligomerization
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