NKD1

Description		NKD inhibitor of Wnt signaling pathway 1
Image		No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Cytoplasm Plasma Membrane Membrane
	Molecular Function	Calcium Ion Binding Protein Binding PDZ Domain Binding Metal Ion Binding
	Biological Process	Eye Photoreceptor Cell Differentiation Axis Elongation Somatic Muscle Development Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Catabolic Process Convergent Extension Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Migration Involved In Somitogenic Axis Elongation Positive Regulation Of Non-canonical Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways
Drugs
Diseases
GWAS		Copper levels ( 26025379) Crohn's disease ( 22412388 28067908) Inflammatory bowel disease ( 28067908) Systolic blood pressure ( 30224653)
Novel Interacting Genes		15 novel interacting genes: AKT1 CYSRT1 DVL3 KRTAP10-1 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 KRTAP9-8 MDFI MORF4L1
Interacting Genes		15 interacting genes: AKT1 CYSRT1 DVL3 KRTAP10-1 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 KRTAP9-8 MDFI MORF4L1
Entrez ID		85407
HPRD ID		08482
Ensembl ID		ENSG00000140807
Uniprot IDs		Q969G9
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Cytosol
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