NDST2

Description		N-deacetylase and N-sulfotransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Catalytic Activity Sulfotransferase Activity Heparan Sulfate N-sulfotransferase Activity Transferase Activity Hydrolase Activity Deacetylase Activity N-acetylglucosamine Deacetylase Activity Heparan Sulfate N-deacetylase Activity
	Biological Process	Regulation Of Angiotensin Levels In Blood Mast Cell Mediated Immunity Heparan Sulfate Proteoglycan Biosynthetic Process Heparin Proteoglycan Biosynthetic Process
Pathways		HS-GAG biosynthesis
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Crohn's disease ( 28067908)
Novel Interacting Genes		1 novel interacting genes: TNFRSF14
Interacting Genes		1 interacting genes: TNFRSF14
Entrez ID		8509
HPRD ID		04465
Ensembl ID		ENSG00000166507
Uniprot IDs		B4E139 P52849 S4R438
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Adaptive Immune Memory Response Tumor Necrosis Factor Receptor Activity Negative Regulation Of Alpha-beta T Cell Proliferation Positive Regulation Of T Cell Migration Positive Regulation Of Lymphocyte Migration T Cell Costimulation Regulation Of T Cell Migration Cytokine Binding Negative Regulation Of Alpha-beta T Cell Activation Negative Regulation Of T Cell Proliferation Positive Regulation Of Mononuclear Cell Migration Negative Regulation Of Leukocyte Proliferation Negative Regulation Of Lymphocyte Proliferation Regulation Of Lymphocyte Migration Positive Regulation Of Cytokine Production Involved In Immune Response Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Mononuclear Cell Proliferation Defense Response To Gram-negative Bacterium Virus Receptor Activity Negative Regulation Of Adaptive Immune Response Defense Response To Gram-positive Bacterium Receptor Ligand Activity Regulation Of Alpha-beta T Cell Activation Regulation Of Cytokine Production Involved In Immune Response Symbiont Entry Into Host Cell Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Migration Negative Regulation Of T Cell Activation Negative Regulation Of Leukocyte Cell-cell Adhesion Biological Process Involved In Interaction With Host Negative Regulation Of Lymphocyte Activation Regulation Of Production Of Molecular Mediator Of Immune Response Regulation Of T Cell Proliferation Negative Regulation Of Leukocyte Activation Regulation Of Leukocyte Migration Negative Regulation Of Immune Response Negative Regulation Of Cell Activation Negative Regulation Of Cell-cell Adhesion Regulation Of Adaptive Immune Response Regulation Of Mononuclear Cell Proliferation Positive Regulation Of T Cell Activation Positive Regulation Of Immune Effector Process Regulation Of Leukocyte Proliferation Positive Regulation Of Leukocyte Cell-cell Adhesion Adaptive Immune Response Defense Response To Bacterium Ubiquitin Protein Ligase Binding Negative Regulation Of Cell Adhesion Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion
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