PIGY

Description		phosphatidylinositol glycan anchor biosynthesis class Y
Image		No pdb structure
GO Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane
	Molecular Function	Protein Binding Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	GPI Anchor Biosynthetic Process
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Bipolar disorder ( 22925353) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Novel Interacting Genes		5 novel interacting genes: ABCB4 ERG28 FBXO7 PIGA TMEM72
Interacting Genes		5 interacting genes: ABCB4 ERG28 FBXO7 PIGA TMEM72
Entrez ID		84992
HPRD ID		17492
Ensembl ID		ENSG00000255072
Uniprot IDs		Q3MUY2
PDB IDs
Enriched GO Terms of Interacting Partners?		Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Cellular Response To Bile Acid Response To Fenofibrate Ceramide Floppase Activity Ceramide Translocation Lewy Body Core Intercellular Canaliculus Positive Regulation Of Phospholipid Translocation Bile Acid Secretion Sphingolipid Translocation Response To Bile Acid Phosphatidylcholine Floppase Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Lipid Metabolic Process ATPase-coupled Intramembrane Lipid Transporter Activity Positive Regulation Of Phospholipid Transport Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Tagcloud ?