ATOH8

Description		atonal bHLH transcription factor 8
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Dimerization Activity E-box Binding DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Formation Of Primary Germ Layer Negative Regulation Of Endothelial Cell Proliferation Nervous System Development Anatomical Structure Morphogenesis Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Gene Expression Cell Differentiation Tube Formation Positive Regulation Of Endothelial Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Formation Involved In Morphogenesis Myoblast Proliferation Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of MiRNA Transcription
Pathways
Drugs
Diseases
GWAS		Blood metabolite levels ( 31502714) Optic disc size ( 31809533)
Novel Interacting Genes		1 novel interacting genes: CYP3A5
Interacting Genes		1 interacting genes: CYP3A5
Entrez ID		84913
HPRD ID		09813
Ensembl ID		ENSG00000168874
Uniprot IDs		Q96SQ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Lipid Hydroxylation Testosterone 6-beta-hydroxylase Activity Estrogen 16-alpha-hydroxylase Activity Oxidative Demethylation Alkaloid Catabolic Process Aflatoxin Metabolic Process Estrogen 2-hydroxylase Activity Retinoic Acid 4-hydroxylase Activity Alkaloid Metabolic Process Demethylation Toxin Metabolic Process Retinoic Acid Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Oxygen Binding Xenobiotic Catabolic Process Estrogen Metabolic Process Secondary Metabolic Process Retinol Metabolic Process Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Monooxygenase Activity Retinoid Metabolic Process Diterpenoid Metabolic Process Terpenoid Metabolic Process Isoprenoid Metabolic Process Xenobiotic Metabolic Process Iron Ion Binding Heme Binding Olefinic Compound Metabolic Process Intracellular Membrane-bounded Organelle Lipid Modification Hormone Metabolic Process Steroid Metabolic Process Alcohol Metabolic Process Monocarboxylic Acid Metabolic Process Oxidoreductase Activity Regulation Of Hormone Levels
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