CBR4

Description		carbonyl reductase 4
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Oxidoreductase Complex
	Molecular Function	NAD(P)H Dehydrogenase (quinone) Activity 3-oxoacyl-[acyl-carrier-protein] Reductase (NADPH) Activity Protein Binding NADPH Dehydrogenase (quinone) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Quinone Binding NADPH Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Daunorubicin Metabolic Process Doxorubicin Metabolic Process Fatty-acyl-CoA Biosynthetic Process Protein Homotetramerization Protein Heterotetramerization
Pathways		Fatty acyl-CoA biosynthesis
Drugs
Diseases
GWAS		Photic sneeze reflex ( 27182965)
Novel Interacting Genes		2 novel interacting genes: CFTR ZXDC
Interacting Genes		2 interacting genes: CFTR ZXDC
Entrez ID		84869
HPRD ID		07859
Ensembl ID		ENSG00000145439
Uniprot IDs		Q8N4T8
PDB IDs		4CQL 4CQM
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization LRR Domain Binding Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane C2H2 Zinc Finger Domain Binding Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane Odontogenesis Of Dentin-containing Tooth Chloride Channel Activity Multicellular Organismal-level Chemical Homeostasis Regulation Of Cellular PH Regulation Of Transmembrane Transporter Activity
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