PLCD4

Description		phospholipase C delta 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane
	Molecular Function	G-protein Alpha-subunit Binding Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding Phosphoric Diester Hydrolase Activity Hydrolase Activity Metal Ion Binding Phosphatidylinositol Phospholipase C Activity
	Biological Process	Lipid Metabolic Process Signal Transduction Small GTPase-mediated Signal Transduction Acrosome Reaction Lipid Catabolic Process Intracellular Signal Transduction
Pathways		Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Height ( 25429064) Male-pattern baldness ( 28196072)
Novel Interacting Genes		5 novel interacting genes: APP IPO11 MEOX1 MEOX2 TRIM39
Interacting Genes		5 interacting genes: APP IPO11 MEOX1 MEOX2 TRIM39
Entrez ID		84812
HPRD ID		07296
Ensembl ID		ENSG00000115556
Uniprot IDs		C9JEA7 Q9BRC7
PDB IDs
Enriched GO Terms of Interacting Partners?		Somite Specification Segment Specification Somite Development Embryonic Pattern Specification Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Positive Regulation Of Apoptotic Signaling Pathway Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Sclerotome Development Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Ribosomal Protein Import Into Nucleus Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Epithelium Development Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle
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