OFD1

Description		OFD1 centriole and centriolar satellite protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Membrane Motile Cilium Centriolar Satellite Ciliary Basal Body Cell Projection
	Molecular Function	Protein Binding Identical Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding Molecular Adaptor Activity
	Biological Process	Mitotic Cell Cycle Centriole Replication Embryonic Body Morphogenesis Cell Projection Organization Axoneme Assembly Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases		Oral-facial-digital syndrome 1 Joubert syndrome
GWAS
Novel Interacting Genes		11 novel interacting genes: AKT1 CCSER2 CEP126 EGFL6 EIF6 GPRASP1 LUC7L2 NME7 RAI2 RUVBL1 S100A6
Interacting Genes		11 interacting genes: AKT1 CCSER2 CEP126 EGFL6 EIF6 GPRASP1 LUC7L2 NME7 RAI2 RUVBL1 S100A6
Entrez ID		8481
HPRD ID		02162
Ensembl ID		ENSG00000046651
Uniprot IDs		E9KL37 O75665
PDB IDs
Enriched GO Terms of Interacting Partners?
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