PLEKHA8

Description		pleckstrin homology domain containing A8
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GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane
	Molecular Function	Protein Binding Lipid Binding Glycolipid Transfer Activity Glycolipid Binding Phosphatidylinositol-4-phosphate Binding Ceramide Binding Lipid Transfer Activity Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity
	Biological Process	Lipid Transport Protein Transport ER To Golgi Ceramide Transport Ceramide Transport Glycolipid Transport Intermembrane Lipid Transfer Ceramide 1-phosphate Transport
Pathways		Synthesis of PIPs at the plasma membrane Glycosphingolipid transport
Drugs
Diseases
GWAS		Estradiol levels ( 22675492) Glucocorticoid receptor gene expression in B-cell precursor acute lymphoblastic leukaemia ( 33002292)
Novel Interacting Genes		1 novel interacting genes: ARF1
Interacting Genes		1 interacting genes: ARF1
Entrez ID		84725
HPRD ID		10555
Ensembl ID		ENSG00000106086
Uniprot IDs		A0A087X1S6 A0A2P1JJM6 B5MDU3 Q96JA3
PDB IDs		5KDI
Enriched GO Terms of Interacting Partners?		Mitotic Cleavage Furrow Ingression Cleavage Furrow Ingression Mitotic Cytokinetic Process Neuron Projection Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Intracellular Copper Ion Homeostasis Dendritic Spine Organization Postsynapse Organization Membrane Invagination Copper Ion Homeostasis Long-term Synaptic Depression Negative Regulation Of Synaptic Transmission Cytokinetic Process Regulation Of Actin Nucleation Sarcomere Cell Leading Edge Regulation Of Receptor Internalization Cellular Response To Virus Regulation Of Receptor-mediated Endocytosis
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