HINT2

Description		histidine triad nucleotide binding protein 2
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix
	Molecular Function	Nucleotide Binding Catalytic Activity Protein Binding Hydrolase Activity Adenosine 5'-monophosphoramidase Activity
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Apoptotic Process Lipid Catabolic Process
Pathways		RHOD GTPase cycle
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)
Novel Interacting Genes		2 novel interacting genes: APP CFTR
Interacting Genes		2 interacting genes: APP CFTR
Entrez ID		84681
HPRD ID		17106
Ensembl ID		ENSG00000137133
Uniprot IDs		Q9BX68
PDB IDs		4INC 4INI 5KM5 5KM8 5KM9 6YI0 6YPR 6YPX 6YQD 6YVP
Enriched GO Terms of Interacting Partners?		Protein-folding Chaperone Binding Amyloid-beta Complex Response To Purine-containing Compound Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Recycling Endosome Amylin Binding Cell Maturation Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Response To CAMP Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Early Endosome Membrane Developmental Maturation Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Establishment Of Protein Localization Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Early Endosome Growth Cone Filopodium Regulation Of Monoatomic Ion Transmembrane Transport Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Transport Positive Regulation Of Anion Channel Activity Positive Regulation Of Monoatomic Anion Transport Response To Norepinephrine Intracellular Monoatomic Cation Homeostasis Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Monoatomic Ion Transport Enzyme Binding Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Intracellular Monoatomic Ion Homeostasis Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Enamel Mineralization Transepithelial Water Transport
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