IL1F10

Description		interleukin 1 family member 10
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Cytokine Activity Interleukin-1 Receptor Binding Protein Binding
	Biological Process	Inflammatory Response Immune Response Cytokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways		Interleukin-38 signaling Interleukin-36 pathway
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874 33547301) C-reactive protein ( 22939635) C-reactive protein levels ( 33339817 21300955 30388399) C-reactive protein levels or LDL-cholesterol levels (pleiotropy) ( 27286809) C-reactive protein levels or total cholesterol levels (pleiotropy) ( 27286809) C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809) Coronary artery disease ( 29212778) Dysmenorrheic pain ( 27454463) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422 26561523) Inflammatory biomarkers ( 24182552) Interleukin-1-receptor antagonist levels ( 22205395) Interleukin-6 levels ( 33517400) Low density lipoprotein cholesterol levels ( 32154731) Myocardial infarction ( 33532862) Serum alkaline phosphatase levels ( 33547301) Stroke ( 26089329) Total cholesterol levels ( 29083408)
Novel Interacting Genes		2 novel interacting genes: IL1R1 IMPDH2
Interacting Genes		2 interacting genes: IL1R1 IMPDH2
Entrez ID		84639
HPRD ID		17144
Ensembl ID		ENSG00000136697
Uniprot IDs		Q8WWZ1
PDB IDs		5BOW
Enriched GO Terms of Interacting Partners?		Interleukin-1 Binding Smooth Muscle Adaptation Response To Peptide Positive Regulation Of Neutrophil Extravasation Regulation Of Neutrophil Extravasation Interleukin-1, Type I, Activating Receptor Activity Positive Regulation Of Interleukin-1-mediated Signaling Pathway Response To Cytokine Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Interleukin-1 Receptor Activity Positive Regulation Of T-helper 1 Cell Cytokine Production GTP Biosynthetic Process 'de Novo' XMP Biosynthetic Process IMP Dehydrogenase Activity Regulation Of Interleukin-1-mediated Signaling Pathway Platelet-derived Growth Factor Receptor Binding GMP Biosynthetic Process NAD+ Nucleosidase Activity, Cyclic ADP-ribose Generating Positive Regulation Of Cellular Extravasation Positive Regulation Of T-helper 1 Type Immune Response Purine Ribonucleoside Monophosphate Biosynthetic Process GTP Metabolic Process Cellular Response To Interleukin-4 Interleukin-1-mediated Signaling Pathway Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Response To Interleukin-4 GMP Metabolic Process Positive Regulation Of T Cell Cytokine Production Positive Regulation Of Neutrophil Migration Ribonucleoside Monophosphate Biosynthetic Process Regulation Of Cellular Extravasation Regulation Of T Cell Cytokine Production Regulation Of Neutrophil Migration Nucleoside Monophosphate Biosynthetic Process Cytokine Receptor Activity Positive Regulation Of Cytokine-mediated Signaling Pathway Peroxisomal Membrane Positive Regulation Of Response To Cytokine Stimulus Positive Regulation Of Type II Interferon Production Positive Regulation Of T Cell Mediated Immunity Nucleoside Monophosphate Metabolic Process Response To Interleukin-1 Positive Regulation Of Cytokine Production Involved In Immune Response Immune System Process Nucleoside Triphosphate Biosynthetic Process Regulation Of T Cell Mediated Immunity Protease Binding Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Type II Interferon Production Extracellular Region
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