DCUN1D5

Description		defective in cullin neddylation 1 domain containing 5
Image		No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm Spindle Cytoskeleton
	Molecular Function	Protein Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Binding Cullin Family Protein Binding
	Biological Process	Regulation Of Cell Growth DNA Damage Response Protein Neddylation Regulation Of Protein Neddylation Positive Regulation Of Protein Neddylation
Pathways		Neddylation
Drugs
Diseases
GWAS		Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Diisocyanate-induced asthma ( 25918132) Interleukin-10 levels ( 22205395) Toenail selenium levels ( 25343990) Tuberculosis ( 24057671)
Novel Interacting Genes		11 novel interacting genes: CAND1 CHUK CUL2 CUL3 HUS1 LNX1 PICK1 PLEKHG4 RCHY1 UBE2F UBE2M
Interacting Genes		11 interacting genes: CAND1 CHUK CUL2 CUL3 HUS1 LNX1 PICK1 PLEKHG4 RCHY1 UBE2F UBE2M
Entrez ID		84259
HPRD ID		14520
Ensembl ID		ENSG00000137692
Uniprot IDs		B4DP84 Q9BTE7
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Cullin-RING Ubiquitin Ligase Complex Post-translational Protein Modification Ubiquitin-protein Transferase Activity NEDD8 Conjugating Enzyme Activity Protein Modification Process NEDD8 Transferase Activity Ubiquitin Ligase Complex Scaffold Activity Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Ubiquitination Proteolysis Involved In Protein Catabolic Process Cytosol Protein Metabolic Process Protein Neddylation Macromolecule Catabolic Process Macromolecule Metabolic Process Postsynapse Proteolysis Response To Acetate Protein Autoubiquitination Response To Cholecystokinin Meiotic DNA Integrity Checkpoint Signaling Trophectodermal Cellular Morphogenesis Cell Cycle G1/S Phase Transition Liver Morphogenesis G1/S Transition Of Mitotic Cell Cycle Ubiquitin Protein Ligase Activity SCF Complex Assembly Positive Regulation Of Type I Interferon Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process IkappaB Kinase Activity Regulation Protein Catabolic Process At Postsynapse Positive Regulation Of Protein Ubiquitination Ubiquitin Ligase Complex Response To Amino Acid POZ Domain Binding Membrane Curvature Sensor Activity NEDD8 Ligase Activity Regulation Of Type I Interferon Production Transferase Activity Checkpoint Clamp Complex Positive Regulation Of Post-translational Protein Modification Polar Microtubule Proteasomal Protein Catabolic Process Error-free Translesion Synthesis Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Mitotic Cell Cycle Phase Transition Nucleoplasm
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