SYDE2

Description		synapse defective Rho GTPase homolog 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Synaptic Membrane
	Molecular Function	GTPase Activator Activity
	Biological Process	Signal Transduction Cell Migration Regulation Of Ras Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity
Pathways		RAC1 GTPase cycle
Drugs
Diseases
GWAS		Body mass index ( 28552196) Longevity ( 30294719) Multiple sclerosis ( 31604244)
Novel Interacting Genes		1 novel interacting genes: RAC1
Interacting Genes		1 interacting genes: RAC1
Entrez ID		84144
HPRD ID		19360
Ensembl ID		ENSG00000097096
Uniprot IDs		Q5VT97
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Ovarian Follicle Development Negative Regulation Of Interleukin-23 Production Regulation Of ERK5 Cascade Angiotensin-activated Signaling Pathway Involved In Heart Process Embryonic Olfactory Bulb Interneuron Precursor Migration Cerebral Cortex GABAergic Interneuron Development Rho GDP-dissociation Inhibitor Binding Regulation Of Cell Adhesion Involved In Heart Morphogenesis Kinocilium Positive Regulation Of Bicellular Tight Junction Assembly Regulation Of Interleukin-23 Production Regulation Of Ovarian Follicle Development G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Auditory Receptor Cell Morphogenesis Regulation Of Neuron Maturation Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Thioesterase Binding Erythrocyte Enucleation Hepatocyte Growth Factor Receptor Signaling Pathway Engulfment Of Apoptotic Cell Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Tangential Migration From The Subventricular Zone To The Olfactory Bulb Positive Regulation Of Receptor Clustering Negative Regulation Of Fibroblast Migration Midbrain Dopaminergic Neuron Differentiation Ruffle Assembly Regulation Of Hydrogen Peroxide Metabolic Process NADPH Oxidase Complex Sphingosine-1-phosphate Receptor Signaling Pathway Sphingolipid Mediated Signaling Pathway Positive Regulation Of Ruffle Assembly Interneuron Migration Angiotensin-activated Signaling Pathway Rac Protein Signal Transduction Hyperosmotic Response Respiratory Burst Cochlea Morphogenesis Regulation Of Ruffle Assembly Dopaminergic Neuron Differentiation Positive Regulation Of Neutrophil Migration Negative Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Lamellipodium Assembly Cerebral Cortex Cell Migration Phagocytic Cup Regulation Of Cell Maturation Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Rho Protein Signal Transduction Regulation Of Bicellular Tight Junction Assembly Motor Neuron Axon Guidance Positive Regulation Of Granulocyte Chemotaxis
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