ARL6

Description		ARF like GTPase 6
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Axonemal Microtubule Plasma Membrane Cilium Axoneme Microtubule Cytoskeleton Membrane Membrane Coat Cell Projection Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding
	Biological Process	Protein Targeting To Membrane Intracellular Protein Transport Determination Of Left/right Symmetry Brain Development Visual Perception Regulation Of Smoothened Signaling Pathway Retina Layer Formation Protein Transport Wnt Signaling Pathway Vesicle-mediated Transport Cell Projection Organization Melanosome Transport Fat Cell Differentiation Protein Polymerization Cilium Assembly Protein Localization To Cilium Protein Localization To Non-motile Cilium Protein Transport From Ciliary Membrane To Plasma Membrane
Pathways		BBSome-mediated cargo-targeting to cilium
Drugs
Diseases		Bardet-Biedl syndrome (BBS) Retinitis pigmentosa (RP)
GWAS		Male infertility ( 19478329)
Novel Interacting Genes		12 novel interacting genes: ARL13B ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 CEBPD CRYBG3 GLS PROS1 SEC61B SYNRG
Interacting Genes		12 interacting genes: ARL13B ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 CEBPD CRYBG3 GLS PROS1 SEC61B SYNRG
Entrez ID		84100
HPRD ID		10588
Ensembl ID		ENSG00000113966
Uniprot IDs		Q9H0F7
PDB IDs		2H57
Enriched GO Terms of Interacting Partners?		Regulation Of L-glutamate Import Across Plasma Membrane Sec61 Translocon Complex Endoplasmic Reticulum Tubular Network Membrane Organization Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Tubular Network Organization Cellular Localization Endoplasmic Reticulum Membrane Endoplasmic Reticulum Sec Complex Endoplasmic Reticulum Organization Negative Regulation Of L-glutamate Import Across Plasma Membrane Regulation Of Amine Transport
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